LabCompass

Jonathan P. Schlebach

Biochemistry, Genetics and Molecular Biology · Indiana University

OpenAlex ORCID
RNA and protein synthesis mechanismsPhotoreceptor and optogenetics researchCellular transport and secretionReceptor Mechanisms and SignalingCystic Fibrosis Research Advances

Publications

81

Citations

1,267

Est. group size

~7

Recurring co-author estimate

Active years

17

Publishing since 2010

Research summary
AI-generated

Jonathan P. Schlebach studies how membrane proteins fold, misfold, and move through the cell, and how genetic variants disrupt these processes to cause disease. A major focus is cystic fibrosis, including the biochemistry of the CFTR protein and how drugs (pharmacological chaperones) can correct defective protein folding. The work combines molecular biophysics with computational tools for predicting the effects of disease-causing mutations.

Membrane protein folding and misfoldingCystic fibrosis and CFTR biologyPharmacological chaperones and drug discoveryProtein trafficking and cellular quality controlGenetic variant effect prediction

Publication activity has grown over the last decade, rising from about one per year in 2017 to roughly 8-12 per year in recent years.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence
Publications per year over the last 10 years — averaging 8.4/year recently
2017: 1 publication172018: 3 publications182019: 4 publications192020: 8 publications202021: 9 publications212022: 6 publications222023: 10 publications232024: 8 publications242025: 12 publications12252026: 6 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×18
  • Journal of Biological Chemistry×7
  • eLife×7
  • Biophysical Journal×6
  • Biochemistry×3

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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