Publications
33
Citations
358
Est. group size
~3
Recurring co-author estimate
Active years
27
Publishing since 1998
John V. Napoleon works in medicinal chemistry, designing and testing small molecules that target specific proteins involved in diseases such as cancer, malaria, and bacterial infections. Much of the work involves synthesizing chemical compounds, determining their crystal structures, and evaluating how they inhibit disease-related enzymes like IKKβ, CDPK1, and CDK9. This research is preclinical (lab-based), aimed at identifying candidate drug molecules rather than testing them in patients.
Publication output grew from essentially none in 2017-2018 to a peak of around 5-6 papers per year in 2021-2023, followed by a decline in 2024-2025, suggesting a period of increased activity followed by a recent slowdown.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Biological evaluation of novel side chain containing CQTrICh-analogs as antimalarials and their development as PfCDPK1 kinase inhibitors
Heliyon · 2024
- Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth
Proceedings of the National Academy of Sciences · 2022
- Biological evaluation of novel side chain containing CQTrICh-analogs as antimalarials and their development as <i>Pf</i> CDPK1 kinase inhibitors
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner
Chemical Communications · 2021
- Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy
European Journal of Medicinal Chemistry · 2021
- CCDC 2089611: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2021
- CCDC 2089610: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2021
- N‐Substituted 1,2,3‐Triazolyl‐Appended Indole‐Chalcone Hybrids as Potential DNA Intercalators Endowed with Antioxidant and Anticancer Properties
ChemistrySelect · 2018
- Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy
Journal of Medicinal Chemistry · 2016
- FtsZ inhibition and redox modulation with one chemical scaffold: Potential use of dihydroquinolines against mycobacteria
European Journal of Medicinal Chemistry · 2016
- Cancer Research×4
- Frontiers in Immunology×3
- European Journal of Medicinal Chemistry×2
- The Cambridge Structural Database×2
- Journal of Medicinal Chemistry×1
- Mark P. Rubinstein
Medicine · The Ohio State University
- Chunyu Xu
Medicine · Purdue University West Lafayette
- Bihui Cao
Medicine · Indiana University
- Lynn O’Donnell
Medicine · The Ohio State University
- Jay K. Mandula
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile