LabCompass

John V. Napoleon

Medicine · Purdue University West Lafayette

Established · publishing since 1998

Publications

33

Citations

358

Est. group size

~3

Recurring co-author estimate

Active years

27

Publishing since 1998

Research summary
AI-generated

John V. Napoleon works in medicinal chemistry, designing and testing small molecules that target specific proteins involved in diseases such as cancer, malaria, and bacterial infections. Much of the work involves synthesizing chemical compounds, determining their crystal structures, and evaluating how they inhibit disease-related enzymes like IKKβ, CDPK1, and CDK9. This research is preclinical (lab-based), aimed at identifying candidate drug molecules rather than testing them in patients.

Small-molecule drug design and synthesisKinase inhibitor development (IKKβ, CDPK1, CDK9)Antimalarial and antimicrobial compound researchCancer therapeutics (pancreatic cancer focus)Structure-activity relationship and crystal structure studies

Publication output grew from essentially none in 2017-2018 to a peak of around 5-6 papers per year in 2021-2023, followed by a decline in 2024-2025, suggesting a period of increased activity followed by a recent slowdown.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.8/year recently
172018: 1 publication182019: 2 publications192020: 2 publications202021: 5 publications212022: 6 publications6222023: 6 publications6232024: 2 publications242526
Publishes in
  • Cancer Research×4
  • Frontiers in Immunology×3
  • European Journal of Medicinal Chemistry×2
  • The Cambridge Structural Database×2
  • Journal of Medicinal Chemistry×1
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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