Jixing Lyu
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
37
Citations
210
Est. group size
~1
Recurring co-author estimate
Active years
6
Publishing since 2020
Jixing Lyu studies how membrane proteins and other large protein complexes work at the molecular level, using a technique called native mass spectrometry that weighs intact proteins while preserving their natural interactions. A major focus is on membrane transporter proteins (such as the ABC transporter MsbA) and how lipids and metal ions like copper and zinc regulate their activity. The work often combines mass spectrometry with structural methods like cryo-electron microscopy to reveal how these proteins are activated or controlled.
Publication activity grew steadily from 2020, peaked around 2023-2024, and averages about 6 publications per year over the last five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Molecular basis for the activation of <i>Pseudomonas aeruginosa</i> MsbA by Zn <sup>2+</sup>
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Molecular Basis for the Activation of <i>Pseudomonas aeruginosa</i> MsbA by Divalent Metals
Journal of the American Chemical Society · 2025
- Symmetry facilitated the evolution of heterospecificity and high-order stoichiometry in vertebrate hemoglobin
Proceedings of the National Academy of Sciences · 2025
- Real time characterization of the MAPK pathway using native mass spectrometry
Communications Biology · 2025
- Single-particle cryoEM data of copper-loaded ABC transporter MsbA
EMPIAR dataset · 2024
- Single-particle cryoEM data of copper-loaded ABC transporter MsbA trapped with ADP-vanadate
EMPIAR dataset · 2024
- Advances and challenges in preparing membrane proteins for native mass spectrometry
Biotechnology Advances · 2024
- Native mass spectrometry and structural studies reveal modulation of MsbA–nucleotide interactions by lipids
Nature Communications · 2024
- Symmetry facilitated the evolution of heterospecificity and high-order stoichiometry in vertebrate hemoglobin
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Single-particle cryoEM data of copper-loaded ABC transporter MsbA in the presence of ATP for 6 hours
EMPIAR dataset · 2024
- CXSPM_mass_spec_data
Zenodo (CERN European Organization for Nuclear Research) · 2023
- CXSPM_mass_spec_data
Zenodo (CERN European Organization for Nuclear Research) · 2023
- Polyamine detergents tailored for native mass spectrometry studies of membrane proteins
Nature Communications · 2023
- Cardiolipin Regulates the Activity of the Mitochondrial ABC Transporter ABCB10
Biochemistry · 2023
- Structural basis for lipid and copper regulation of the ABC transporter MsbA
Zenodo (CERN European Organization for Nuclear Research) · 2022
- Zenodo (CERN European Organization for Nuclear Research)×6
- bioRxiv (Cold Spring Harbor Laboratory)×4
- Nature Communications×3
- eLife×3
- EMPIAR dataset×3
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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