Jiajie Yan

Jiajie Yan's research investigates the molecular mechanisms underlying heart rhythm disorders, particularly atrial fibrillation (an irregular, often rapid heartbeat), and how stress signaling pathways inside heart cells contribute to arrhythmias, alcohol-related heart problems, and thrombosis (blood clot formation). Much of the work centers on a stress-activated enzyme called JNK2 and its role in communication between the heart and other organs (gut, brain, platelets), as well as calcium and zinc handling within heart muscle cells. This research combines cellular and animal models to identify potential drug targets for treating or preventing arrhythmias linked to aging, alcohol consumption, and emotional stress.

Publication output has grown over the last decade, rising from about 1-3 papers per year before 2020 to a peak of 8 in 2024, indicating an increasingly active research program.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026