Jeffrey S. Elmendorf
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
77
Citations
3,055
Est. group size
—
Recurring co-author estimate
Active years
32
Publishing since 1994
Jeffrey S. Elmendorf studies how the body's cells take up and process glucose (blood sugar) and how this goes wrong in insulin resistance, a key feature of type 2 diabetes. His work focuses especially on skeletal muscle, examining how factors like cholesterol buildup in cell membranes, actin (the cell's structural scaffolding), and signaling proteins such as PAK1 affect glucose uptake. He also investigates how diet, exercise, and medications influence these metabolic processes.
Publication activity was highest around 2017 and has slowed to roughly one paper per year in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through May 2030 — about 4 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Pilot & Feasibility Program
3 earlier awards
- NIH R01DK114222Aug 2018 – Jun 2021 · $394k awarded
Cholesterol Toxicity as a Promising Target for Diabetes Prevention
- NIH R01DK082773Mar 2009 – Jan 2014 · $328k awarded
Mechanisms of Membrane-Based Insulin Resistance & Therapeutic Reversal Strategies
- NIH R01AT001846Aug 2004 – May 2010 · $271k awarded
CHROMIUM ENHANCES INSULIN & GLUT4 ACTION VIA LIPID RAFTS
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~7 · 20% small-team papers (≤3 authors) · across 10 venues
- Evidence for a novel, reversible mechanism of mitochondrial dysfunction in insulin-resistant skeletal muscle
Physiology · 2025
- An early, reversible cholesterolgenic etiology of diet-induced insulin resistance
Molecular Metabolism · 2023
- Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis
Frontiers in Endocrinology · 2022
- Unifying mechanisms of trivalent chromium in health and disease
Elsevier eBooks · 2020
- Contributors
Elsevier eBooks · 2020
- Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet
American Journal of Physiology-Endocrinology and Metabolism · 2019
- 266-LB: Evidence for a Hexosamine Biosynthesis Pathway-Mediated Sp1 Cholesterolgenic Response Being an Early Etiological Factor of Insulin Resistance
Diabetes · 2019
- Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet
PMC · 2019
- The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)–mediated glucose uptake into skeletal muscle cells
Journal of Biological Chemistry · 2017
- Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western-style high-fat diet
Physiological Reports · 2017
- New Aspects of Cellular Cholesterol Regulation on Blood Glucose Control—Review and Perspective on the Impact of Statin Medications on Metabolic Health
US Endocrinology · 2017
- Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western‐style high‐fat diet
PMC · 2017
- Hexosamine Biosynthesis Pathway Is a Potential Link Between Insulin Resistance and Alzheimer’s Disease
2017
- New aspects of cellular cholesterol regulation on blood glucose control- review and perspective on the impact of statin medications on metabolic health
2017
- The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells
PMC · 2017
- PMC×4
- Elsevier eBooks×2
- Journal of Biological Chemistry×1
- Physiological Reports×1
- Frontiers in Endocrinology×1
- Ishrat Jahan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Gregory D. Cartee
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Edward B. Arias
Biochemistry, Genetics and Molecular Biology · University of Michigan
- John W. Scott
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Xi Song
Medicine · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
Claim or correct this profile