Jean‐Jacques Michaille
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
46
Citations
4,054
Est. group size
—
Recurring co-author estimate
Active years
40
Publishing since 1986
This researcher studies small regulatory molecules called microRNAs, especially one known as miR-155, and how they influence processes like cancer immune responses, inflammation, neurological disease (including Alzheimer's and Down syndrome-related dementia), and spinal cord injury after aortic surgery. The work combines molecular biology with pathology, often examining tissue samples to link microRNA activity to disease outcomes. This research could interest students curious about how a single small RNA molecule can affect very different conditions, from tumors to neurodegeneration.
Publication output has been low and irregular over the last decade, with occasional active years (e.g., 2018) followed by gaps, and a recent average of less than one publication per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- miR-155 aberrant expression impairs tumor rejection because of its targeting of ICOSL and multiple pathways implicated in the antitumor response
Pharmacological Reviews · 2025
- The amplification of CNS damage in Alzheimer's disease due to SARS-CoV2 infection
Annals of Diagnostic Pathology · 2022
- MicroRNA miR-155 Activity in Mouse Choline Acetyltransferase-Positive Neurons Is Critical for the Rate of Early and Late Paraplegia After Transient Aortic Cross-Clamping
Frontiers in Molecular Neuroscience · 2022
- The histologic and molecular correlates of liver disease in fatal COVID-19 including with alcohol use disorder
Annals of Diagnostic Pathology · 2021
- Endovascular repair and open repair surgery of thoraco-abdominal aortic aneurysms cause drastically different types of spinal cord injury
Scientific Reports · 2021
- <i>miR‐155</i>expression in antitumor immunity: The higher the better?
Genes Chromosomes and Cancer · 2018
- microRNA 155 up regulation in the CNS is strongly correlated to Down's syndrome dementia
Annals of Diagnostic Pathology · 2018
- MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis
Annals of Diagnostic Pathology · 2018
- MiR-663, a MicroRNA Linked with Inflammation and Cancer That Is under the Influence of Resveratrol
Medicines · 2018
- Rôles du microARN <b><i>miR-155</i></b> dans les démences associées au syndrome de Down
médecine/sciences · 2018
- MicroRNAs in intestinal barrier function, inflammatory bowel disease and related cancers — their effects and therapeutic potentials
Current Opinion in Pharmacology · 2017
- Promiscuous Effects of Some Phenolic Natural Products on Inflammation at Least in Part Arise from Their Ability to Modulate the Expression of Global Regulators, Namely microRNAs
Molecules · 2016
- Annals of Diagnostic Pathology×4
- Current Opinion in Pharmacology×1
- Molecules×1
- Genes Chromosomes and Cancer×1
- Pharmacological Reviews×1
- Francesca Lovat
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Carlo M. Croce
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Cristian Taccioli
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Esmerina Tili
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Xiaoping Wan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile