James Sledziona
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
11
Citations
148
Est. group size
~2
Recurring co-author estimate
Active years
13
Publishing since 2013
This researcher studies how cells regulate metabolism, fat storage, and programmed cell death, with particular focus on a tumor-suppressor protein called Par-4 and its roles in obesity, cancer, and immune cell function. Work spans techniques from stable-isotope tracing of fatty acid metabolism to studies of immune cell (macrophage) reprogramming in lung cancer tissue. The research connects molecular mechanisms of cancer suppression with metabolic diseases like obesity and diabetes.
Publication output has been irregular over the past decade, with gaps in some years and small clusters of output (1-3 papers) in 2017-2018, 2022, and 2024-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Determination of fatty acid uptake and desaturase activity in mammalian cells by NMR-based stable isotope tracing
Analytica Chimica Acta · 2024
- The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ
Cells · 2024
- Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues
The Journal of Immunology · 2022
- Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity
Frontiers in Oncology · 2022
- Abstract 2537: Beta-glucan reprograms immunomodulatory metabolism in human macrophage and ex vivo in lung cancer tissues
Cancer Research · 2022
- A Novel Role for the Tumor-Suppressor Par-4 in Regulation of Adipogenesis and Obesity
UKnowledge (University of Kentucky) · 2018
- Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis
Cell Reports · 2017
- Regulation of Caspase-Mediated Apoptosis by the Tumor Suppressor Par-4
Resistance to targeted anti-cancer therapeutics · 2017
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Cell Reports×1
- The Journal of Immunology×1
- Analytica Chimica Acta×1
- Cells×1
- Chunhai Hao
Biochemistry, Genetics and Molecular Biology · Indiana University
- Ermias Mekuria Addo
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Anita C. Bellail
Biochemistry, Genetics and Molecular Biology · Indiana University
- Carlo M. Croce
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Jae‐Kyun Ko
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile