James E. Orfila

James E. Orfila studies how the brain is affected by injuries such as stroke and cerebral ischemia (interrupted blood flow to the brain), with particular attention to effects on the hippocampus, a brain region important for memory. His work examines how these injuries disrupt brain plasticity (the brain's ability to adapt and reorganize) and memory, and how factors like sex differences and injury location (e.g., cerebellar stroke) influence recovery, including testing potential treatments like delayed fluoxetine administration.

Publication output has grown over the last decade, rising from a handful of papers per year in 2017-2020 to a notable peak in 2025, though with some year-to-year variability.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026