James A. Williams
Immunology and Microbiology · Indiana University
Publications
161
Citations
4,311
Est. group size
—
Recurring co-author estimate
Active years
57
Publishing since 1970
James A. Williams conducts research in immunology and molecular biology, focusing on the design of DNA-based vaccines and gene therapies as well as the study of protective antibodies against viruses like HIV, SARS-CoV-2, influenza, and varicella zoster. A major thread of the work involves engineering improved non-viral DNA delivery vectors (such as Nanoplasmid systems) to make vaccines and gene therapies safer and more effective. The research also includes structural analysis of viral proteins to guide vaccine design.
Publication output has slowed over the last decade, moving from roughly 8-10 papers per year in 2017-2020 to about 2 per year in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
No award with a current end date on record.
6 earlier awards
- NSF 2433700Jun 2024 – Jun 2025 · $50k awarded
I-Corps: Translation potential of a mobile unit for disaster recovery personnel
- NIH R01DK124776May 2020 – Mar 2024 · $238k awarded
Essential characterization of the Randall's plaque-overgrowth interface
- NIH S10OD016208Sep 2014 – Sep 2015 · $383k awarded
SkyScan 1176 Micro CT System
- NIH R01DK059933Aug 2004 – Aug 2013 · $323k awarded
The Structural Basis of Kidney Stone Fragility
- NIH S10RR023710Mar 2007 – Mar 2008 · $297k awarded
SkyScan 1172 High-resolution desk-top micro-CT system
- NIH R29DK039023Apr 1988 – Mar 1994 · $65k awarded
VOLUME ABSORPTION IN THE RENAL PROXIMAL TUBULE
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~9 · 9% small-team papers (≤3 authors) · across 26 venues
- Structures of the Varicella Zoster Virus Glycoprotein E and Epitope Mapping of Vaccine-Elicited Antibodies
Vaccines · 2024
- Improving cell and gene therapy safety and performance using next-generation Nanoplasmid vectors
Molecular Therapy — Nucleic Acids · 2023
- Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity
Science Advances · 2023
- Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection
Molecular Therapy — Methods & Clinical Development · 2022
- Structural and Computational Design of a SARS-2 Spike Antigen with Increased Receptor Binding Domain Exposure and Improved Immunogenicity
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies
eLife · 2021
- Improved Potency and Safety of DNA-Encoded Antibody Therapeutics Through Plasmid Backbone and Expression Cassette Engineering
Human Gene Therapy · 2021
- Author response: Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies
2021
- Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus
Molecular Therapy — Methods & Clinical Development · 2020
- Novel Non-integrating DNA Nano-S/MAR Vectors Restore Gene Function in Isogenic Patient-Derived Pancreatic Tumor Models
Molecular Therapy — Methods & Clinical Development · 2020
- Angiogenic and immunomodulatory biomarkers in axitinib-treated patients with advanced renal cell carcinoma
Future Oncology · 2020
- Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes
Proceedings of the National Academy of Sciences · 2019
- Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage
Nature Communications · 2019
- Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors
Proteins Structure Function and Bioinformatics · 2019
- Journal of Virology×4
- Poster presentations×4
- Journal of Clinical Microbiology×3
- Molecular Therapy — Methods & Clinical Development×3
- Sexually Transmitted Diseases×3
- Stephen J. Jordan
Immunology and Microbiology · Indiana University
- Dennis J. Fortenberry
Immunology and Microbiology · Indiana University
- Caleb M. Ardizzone
Immunology and Microbiology · Indiana University
- Evelyn Toh
Immunology and Microbiology · Indiana University
- David E. Nelson
Immunology and Microbiology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
Claim or correct this profile