Jacy L. Wagnon

Jacy L. Wagnon studies the genetics and molecular biology of epilepsy, focusing on how mutations in ion channel genes (such as SCN8A, SCN1B, and SCN1A) and related proteins disrupt neuron function and cause severe childhood epilepsy syndromes known as developmental and epileptic encephalopathies. Much of this work uses mouse models to understand disease mechanisms and test potential treatments, including gene-targeted therapies like antisense oligonucleotides. This research could interest students wanting to work on the intersection of genetics, neuroscience, and translational epilepsy treatment.

Publication output over the last decade has fluctuated year to year with a peak in 2020, and has slowed somewhat in the most recent years, averaging under two publications per year over the last five years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026