LabCompass

Jack C. Yalowich

Biochemistry, Genetics and Molecular Biology · The Ohio State University

Established · publishing since 1978Rising activity

Publications

173

Citations

5,365

Est. group size

~11

Recurring co-author estimate

Active years

49

Publishing since 1978

Research summary
AI-generated

Jack C. Yalowich's research focuses on how cancer cells respond to and resist chemotherapy drugs, particularly those that damage DNA or target enzymes like topoisomerase II. His recent work examines how natural compounds (such as curcumin) and DNA repair pathways (like the mismatch repair system) influence tumor cell sensitivity to treatment, as well as how immune cells called myeloid-derived suppressor cells affect anticancer drug activity.

Cancer drug resistance mechanismsDNA damage and repairTopoisomerase II inhibitorsNatural compound anticancer activityTumor immune microenvironment

Publication output has grown over the past decade, rising from a single paper in 2017 to a peak of 14 in 2023, though it appears to have leveled off in more recent years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.8/year recently
2017: 1 publication172018: 5 publications182019: 6 publications192020: 3 publications202021: 3 publications212022: 8 publications222023: 14 publications14232024: 3 publications242025: 3 publications252026: 1 publication26
Recent publications
Publishes in
  • Journal of Pharmacology and Experimental Therapeutics×7
  • The FASEB Journal×5
  • Molecular Pharmacology×4
  • ACS Medicinal Chemistry Letters×4
  • Cancer Research×4
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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