J. Alex Pasternak
Agricultural and Biological Sciences · Purdue University West Lafayette
Publications
105
Citations
1,581
Est. group size
~11
Recurring co-author estimate
Active years
55
Publishing since 1972
J. Alex Pasternak studies fetal and reproductive physiology in pigs, focusing on how stress, hormone disruption (especially thyroid hormones), and viral infection during pregnancy affect fetal development. A major focus is porcine reproductive and respiratory syndrome virus (PRRSV), a common pig virus, and how it crosses the placenta to cause fetal illness or death, alongside work on gene expression, hormone signaling, and stress-response pathways in developing piglets. This research aims to understand mechanisms of fetal loss and organ development problems in livestock.
Publication output has grown over the last decade, rising from about 1 paper per year in 2017 to 8-9 per year in 2024-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Weaning stress induced alterations to the hypothalamic‐pituitary‐thyroid and ‐adrenal axes in swine
Physiological Reports · 2026
- Early gestation heat stress influences fetal biomarkers indicative of maternal cortisol transfer in pigs
Scientific Reports · 2025
- Porcine Fetal Hypothyroidism Induces Temporal and Tissue‐Specific Alterations in the Insulin‐Like Growth Factor System
Comprehensive physiology · 2025
- Altered structural and transporter-related gene expression patterns in the placenta play a role in fetal demise during Porcine reproductive and respiratory syndrome virus infection
BMC Genomics · 2025
- Gestational age and fetal hypothyroidism Alter the porcine thyroid and local hepatic and renal renin‐angiotensin systems
Physiological Reports · 2025
- Porcine Reproductive and Respiratory Syndrome Virus (Porcine Arteriviruses)
2025
- Exploring transcriptomic and genomic differences between susceptible and resistant fetal pigs to maternal PRRSV infection at late gestation
Veterinary Research · 2025
- PRRSV-2 viral load in critical non-lymphoid tissues is associated with late gestation fetal compromise
Frontiers in Microbiology · 2024
- Impact of methimazole‐induced hypothyroidism on postnatal swine
Physiological Reports · 2024
- Gene expression in heart, kidney, and liver identifies possible mechanisms underpinning fetal resistance and susceptibility to in utero PRRSV infection
Veterinary Microbiology · 2024
- Late gestation fetal hypothyroidism alters cell cycle regulation across multiple organ systems
BMC Veterinary Research · 2024
- A DIO2 missense mutation and its impact on fetal response to PRRSV infection
BMC Veterinary Research · 2024
- Defining Cellular Diversity at the Swine Maternal-Fetal Interface Using Spatial Transcriptomics and Organoids
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Swine trophoblast organoids as a robust, physiologic model of porcine placental development
Placenta · 2024
- 105 Fetal hypothyroidism dysregulates local hepatic and renal renin-angiotensin systems in a temporal manner
Journal of Animal Science · 2024
- Veterinary Research×4
- Physiological Reports×4
- Journal of Animal Science×4
- BMC Veterinary Research×4
- Veterinary Immunology and Immunopathology×4
- Xiaoyu Niu
Agricultural and Biological Sciences · The Ohio State University
- Sung J. Yoo
Agricultural and Biological Sciences · The Ohio State University
- Ting‐Yu Cheng
Agricultural and Biological Sciences · The Ohio State University
- Roman M. Pogranichniy
Agricultural and Biological Sciences · Purdue University West Lafayette
- Mingde Liu
Agricultural and Biological Sciences · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile