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Irina Artsimovitch

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex ORCID
Established · publishing since 1996
RNA and protein synthesis mechanismsBacterial Genetics and BiotechnologyBacteriophages and microbial interactionsRNA Research and SplicingDNA and Nucleic Acid Chemistry

Publications

212

Citations

9,333

Est. group size

~3

Recurring co-author estimate

Active years

31

Publishing since 1996

Research summary
AI-generated

Irina Artsimovitch studies how bacterial and viral RNA polymerases (the molecular machines that copy DNA into RNA) work, pause, and are regulated, including by specialized proteins that switch shapes ('metamorphic' or 'fold-switching' proteins like RfaH) and by physical forces like DNA supercoiling. This research combines structural biology, biochemistry, and single-molecule biophysics to understand transcription mechanisms in bacteria and in viruses such as SARS-CoV-2, with implications for antibiotic and antiviral drug development.

Transcription mechanisms and RNA polymerase regulationFold-switching ('metamorphic') proteins like RfaHSingle-molecule biophysics of transcriptionDNA supercoiling and protein-DNA interactionsAntibacterial/antiviral drug targets (e.g., pseudouridimycin, viral polymerases)

Publication output has been relatively steady over the past decade, averaging roughly 9-10 papers per year with a peak in 2018 and consistent activity through 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 9.2/year recently
2017: 4 publications172018: 18 publications18182019: 9 publications192020: 10 publications202021: 11 publications212022: 9 publications222023: 11 publications232024: 11 publications242025: 9 publications252026: 6 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×21
  • Biophysical Journal×10
  • Nature Communications×8
  • Nucleic Acids Research×7
  • Molecular Microbiology×5
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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