Howard J. Edenberg
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
854
Citations
56,671
Est. group size
~9
Recurring co-author estimate
Active years
55
Publishing since 1972
Howard J. Edenberg studies the genetics of psychiatric and substance use disorders, using large-scale genome-wide association studies to identify inherited risk factors for conditions like alcohol use disorder, nicotine dependence, and suicidality. His work combines statistical genetics with molecular biology techniques, such as single-cell profiling, to link genetic variants to biological mechanisms in the brain. Much of this research is conducted through large multi-institution collaborations across diverse ancestral populations.
Publication activity has remained steady over the last decade, averaging around 26 papers per year in the most recent five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through June 2027 — about under a year of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Functional genetic variants in substance use disorders
6 earlier awards
- NIH U01AA020892Sep 2011 – Aug 2016 · $225k awarded
Early binge drinking and gene regulation
- NIH R37AA006460Jul 1989 – Apr 2013 · $325k awarded
Structure & Expression of Mammal ALC Dehydrogenase Genes
- NIH R21AA017941Aug 2009 – Jul 2012 · $193k awarded
Elucidating CIS-Acting Elements Regulating Alcohol-Induced Alternative Splicing
- NIH U01AA016660Sep 2006 – Aug 2011 · $174k awarded
Indiana Gene Array Core
- NIH S10RR026805May 2010 – May 2011 · $492k awarded
Applied Biosystems SOLiD 3 System
- NIH R01AA006460Jul 1984 – Jun 2002 · $302k awarded
STRUCTURE & EXPRESSION OF MAMMAL ALC DEHYDROGENASE GENES
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~17 · 4% small-team papers (≤3 authors) · across 83 venues
- Multi-ancestry genome-wide association study and meta-analysis of stimulant use disorder reveals biology and relationships to other psychiatric disorders
medRxiv · 2026
- Regulatory mechanisms driven by functional 3’-UTR variants in alcohol use disorder and related traits
Genome biology · 2026
- Perceived partner substance use, genetic predispositions, and their associations with problematic alcohol use, emotional well-being, and relationship quality
Psychological Medicine · 2026
- Suicidality phenotypes reflect both shared and distinct genetic factors
medRxiv · 2026
- Elevated intron retention implicates neuroinflammation in brains of individuals with alcohol use disorder
Brain Communications · 2026
- Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits
UNC Libraries · 2026
- A systematic review of substance use disorder methylome-wide association studies in postmortem human brain
Translational Psychiatry · 2026
- Polygenic Scores and Mood Disorder Onsets in the Context of Family History and Early Psychopathology
JAMA Network Open · 2025
- Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research
Molecular Psychiatry · 2025
- Mapping the genetic landscape across 14 psychiatric disorders
Nature · 2025
- Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder
Nature Communications · 2025
- Clinical, Genomic, and Neurophysiological Correlates of Lifetime Suicide Attempts among Individuals with an Alcohol Use Disorder
Complex Psychiatry · 2025
- The Psychiatric Genomics Consortium: discoveries and directions
The Lancet Psychiatry · 2025
- Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder
JAMA Network Open · 2025
- Identification of risk variants and cross-disorder pleiotropy through multi-ancestry genome-wide analysis of alcohol use disorder
Nature Mental Health · 2025
- medRxiv×35
- bioRxiv (Cold Spring Harbor Laboratory)×25
- Molecular Psychiatry×22
- European Neuropsychopharmacology×21
- Alcoholism Clinical and Experimental Research×19
- Dongbing Lai
Biochemistry, Genetics and Molecular Biology · Indiana University
- Alex P. Miller
Biochemistry, Genetics and Molecular Biology · Indiana University
- John I. Nürnberger
Biochemistry, Genetics and Molecular Biology · Indiana University
- Marco Abreu
Biochemistry, Genetics and Molecular Biology · Indiana University
- Tae‐Hwi Schwantes‐An
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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