Hongde Li
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
53
Citations
2,179
Est. group size
—
Recurring co-author estimate
Active years
39
Publishing since 1988
Hongde Li studies the molecular and metabolic mechanisms that drive cancer, with a focus on how tumor cells reprogram metabolism (for example, arginine and polyamine pathways) and how signaling proteins such as the Hippo pathway effectors YAP/TAZ control cell growth. The work spans breast cancer, lung cancer, and interactions between tumor cells and immune cells in the surrounding tissue environment. Related projects touch on RNA modifications, cell proliferation signaling, and mass-spectrometry-based measurement of small molecules (metabolomics).
Publication activity has been steady, averaging about four papers per year over the last five years after a dip around 2020–2021.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- MAPK1 phosphorylates CCNB1 at Ser128 to drive mitotic progression and cell proliferation in triple-negative breast cancer
Life Sciences · 2026
- Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
Cancer Cell · 2025
- METTL3-modified exosomes from adipose-derived stem cells enhance the proliferation and migration of dermal fibroblasts by mediating m6A modification of CCNB1 mRNA
Archives of Dermatological Research · 2025
- A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors
Cancer Letters · 2025
- Nuclear PHGDH regulates macrophage polarization through transcriptional repression of GLUD1 and GLS2 in breast cancer
Cancer Biology and Medicine · 2025
- The arginine metabolism battlefield: how metabolite exchange in the tumor microenvironment shapes an immunosuppressive ecosystem
Cancer Biology and Medicine · 2025
- Lactylation in cancer: Current understanding and challenges
Cancer Cell · 2024
- Pulse-shaped high-energy and high-average-power fiber laser in the nanosecond regime
Applied Optics · 2023
- LINC01806 Promotes Breast Cancer Growth and Metastasis via Sponging miR-1286 to Disinhibit ZEB1 Expression
Biochemical Genetics · 2023
- DDX5 maintains cardiac function by regulating CamkII delta alternative splicing
European Heart Journal · 2023
- Multiphase coalescence mediates Hippo pathway activation
Cell · 2022
- YAP/TAZ drives cell proliferation and tumour growth via a polyamine–eIF5A hypusination–LSD1 axis
Nature Cell Biology · 2022
- Landslide susceptibility analysis based on a PSO-DBN prediction model in an earthquake-stricken area
Frontiers in Environmental Science · 2022
- YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP
Genes & Development · 2022
- Peer Review #2 of "Comparison of gut microbiome in the Chinese mud snail (Cipangopaludina chinensis) and the invasive golden apple snail (Pomacea canaliculata) (v0.2)"
2022
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Cancer Cell×2
- Journal of Biological Chemistry×2
- Journal of Visualized Experiments×2
- Cancer Biology and Medicine×2
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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