Guillaume Fiches
Immunology and Microbiology · The Ohio State University
Publications
40
Citations
907
Est. group size
~13
Recurring co-author estimate
Active years
16
Publishing since 2011
Guillaume Fiches studies how viruses such as HIV-1, KSHV (a virus linked to Kaposi sarcoma), and SARS-CoV-2 interact with host cells, particularly how they manipulate the immune system, gene expression, and RNA processing to establish infection or hide dormant (latent) in cells. This work aims to identify host proteins and pathways that could be targeted by drugs to either eliminate hidden viral reservoirs or block viral immune evasion. The research combines molecular virology with cancer biology, since some of these viruses also drive tumor development.
Publication output has fluctuated over the past decade with a gap in 2023 but has picked up again in 2024-2026, suggesting renewed and active output after a temporary slowdown.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomas
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Levosimendan inhibits HIV-1 infection in myeloid cells in the RIOK1-dependent manner
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Levosimendan inhibits HIV-1 infection in myeloid cells in the RIOK1-dependent manner
SSRN Electronic Journal · 2026
- Analysis of head and neck cancer scRNA-seq data identified PRDM6 promotes tumor progression by modulating immune gene expression
Frontiers in Immunology · 2025
- NAT10 Suppresses RNA Sensing Induced IFN-β Transactivation to Promote Viral Infection via Interfering with IRF3 Activities
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Analysis of Head and Neck Cancer scRNA-seq Data Identified PRDM6 Promotes Tumor Progression by Modulating Immune Gene Expression
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- m5C RNA Methylation Is Dysregulated by Oncogenic Herpesviruses via c-Myc Signaling to Counteract Host Antiviral Factors
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Correction: Polyamine biosynthesis and eIF5A hypusination are modulated by the DNA tumor virus KSHV and promote KSHV viral infection
PLoS Pathogens · 2025
- KDM5A/B contribute to HIV-1 latent infection and survival of HIV-1 infected cells
Antiviral Research · 2024
- FACT subunit SUPT16H associates with BRD4 and contributes to silencing of interferon signaling
Nucleic Acids Research · 2022
- SARS-CoV-2 Nsp14 protein associates with IMPDH2 and activates NF-κB signaling
Frontiers in Immunology · 2022
- Polyamine biosynthesis and eIF5A hypusination are modulated by the DNA tumor virus KSHV and promote KSHV viral infection
PLoS Pathogens · 2022
- KDM5A/B promotes HIV-1 latency and KDM5 inhibitors promote HIV-1 lytic reactivation
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination
PLoS Pathogens · 2021
- SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- bioRxiv (Cold Spring Harbor Laboratory)×10
- PLoS Pathogens×5
- Nucleic Acids Research×2
- Frontiers in Immunology×2
- Science Advances×1
- Jian Zhu
Immunology and Microbiology · The Ohio State University
- Netty Santoso
Immunology and Microbiology · The Ohio State University
- Cody J. Warren
Immunology and Microbiology · The Ohio State University
- Sang Hoon Han
Immunology and Microbiology · The Ohio State University
- Tai-Wei Li
Immunology and Microbiology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile