LabCompass

Grace I. Hallinan

Medicine · Indiana University

OpenAlex ORCID
Alzheimer's disease research and treatmentsNeurological diseases and metabolismPrion Diseases and Protein MisfoldingNeuroscience and Neuropharmacology ResearchIntracerebral and Subarachnoid Hemorrhage Research

Publications

32

Citations

1,634

Est. group size

—

Recurring co-author estimate

Active years

9

Publishing since 2017

Research summary
AI-generated

Grace I. Hallinan studies the molecular structures of protein clumps ('filaments' and 'plaques') that build up in the brains of people with neurodegenerative diseases such as Alzheimer's disease, Down syndrome-related dementia, and various tauopathies. Much of the work uses cryo-electron microscopy (cryo-EM), a technique that captures detailed 3D images of these misfolded proteins, and extends into designing synthetic molecules that mimic disease-associated protein shapes. The goal is to understand and classify diseases by the precise structure of their protein aggregates.

Alzheimer's disease and amyloid-beta structuresTau protein filaments and tauopathiesCryo-EM structural biology of the brainProtein misfolding and aggregationStructure-based molecular mimic design

Output has been steady at roughly a few publications per year, with a notable peak in 2021 followed by a return to a consistent cadence (about 2.6 per year over the last five years).

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.6/year recently
2017: 1 publication172018: 3 publications182019: 3 publications192020: 2 publications202021: 10 publications10212022: 4 publications222023: 3 publications232024: 4 publications242025: 2 publications2526
Recent publications
Publishes in
  • Acta Neuropathologica×4
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Nature×2
  • Alzheimer s & Dementia×2
  • Journal of Neuroscience×1

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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