Gian Luca Rampioni Vinciguerra
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
92
Citations
908
Est. group size
~13
Recurring co-author estimate
Active years
41
Publishing since 1986
This researcher studies the molecular mechanisms underlying cancer development and drug resistance, with a particular focus on breast, pancreatic, and ovarian cancers. Their work examines how small RNA molecules (like microRNAs), DNA repair proteins, and cellular metabolism changes contribute to tumor growth and resistance to treatments such as CDK4/6 inhibitors and chemotherapy. Much of the research uses mouse models and patient tissue samples to understand how cancer cells adapt and evade therapy.
Publication output has been variable over the past decade with a sharp spike in 2023, following periods of lower activity, suggesting bursty rather than steadily increasing productivity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- α-ketoglutarate/succinate ratio imbalance impairs thymine DNA glycosylase function and base excision repair process increasing susceptibility to pancreatic cancer
Cell Death and Disease · 2026
- Transcriptional and Epigenetic Plasticity Drive an Alternative Non-clonal Mechanism of Resistance to <i>Kras</i> <sup>G12D</sup> Inhibition in Pancreatic Cancer
Cancer Communications · 2026
- miR-1297 is frequently downmodulated in flat epithelial atypia of the breast and promotes mammary neoplastic transformation via EphrinA2 regulation
Journal of Experimental & Clinical Cancer Research · 2025
- USP1 deubiquitinates PARP1 to regulate its trapping and PARylation activity
Science Advances · 2024
- Loss of the extracellular matrix glycoprotein EMILIN1 accelerates Δ16HER2-driven breast cancer initiation in mice
npj Breast Cancer · 2024
- Platinum-induced upregulation of ITGA6 promotes chemoresistance and spreading in ovarian cancer
EMBO Molecular Medicine · 2024
- A comprehensive luminal breast cancer patient‐derived xenografts ( <scp>PDX</scp> ) library to capture tumor heterogeneity and explore the mechanisms of resistance to <scp>CDK4</scp> /6 inhibitors
The Journal of Pathology · 2024
- Author Correction: Platinum-induced upregulation of ITGA6 promotes chemoresistance and spreading in ovarian cancer
EMBO Molecular Medicine · 2024
- Editorial: Catch me if you can: cellular plasticity in tumor progression and drug resistance
Frontiers in Cell and Developmental Biology · 2024
- Abstract 3354: Capturing tumor heterogeneity to personalize therapy in young patients with hormone receptor positive breast cancer
Cancer Research · 2024
- Loss of <i>CDKN1B</i> induces an age‐related clonal hematopoietic disorder via Notch2 activity dysregulation
Cancer Communications · 2023
- Data from Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis
2023
- Supplementary Tables from Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer
2023
- Supplementary Figures 1-6, Supplementary Materials and Methods from Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer
2023
- Data from Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer
2023
- Cancer Research×8
- EMBO Molecular Medicine×3
- Science Advances×2
- Cell Death and Differentiation×2
- The Journal of Pathology×2
- Rosario Distefano
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Paolo Fadda
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Pierluigi Gasparini
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Giovanni Nigita
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Gianpiero Di Leva
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile