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GeunYoung Sim

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex ORCID
Early career · publishing since 2017Rising activity
MicroRNA in disease regulationRNA Research and SplicingRNA modifications and cancerRNA Interference and Gene DeliveryPlant biochemistry and biosynthesis

Publications

14

Citations

142

Est. group size

~7

Recurring co-author estimate

Active years

9

Publishing since 2017

Research summary
AI-generated

GeunYoung Sim's research spans two distinct areas visible in the publication record: earlier work on engineering bacteria (E. coli) to biosynthesize plant-derived phenolic compounds, and more recent work on RNA splicing-targeted therapies, particularly antisense oligonucleotides (ASOs) that alter gene splicing to disrupt cancer-driving molecular circuits in liver and pancreatic cancer. This suggests a research trajectory that has shifted toward RNA-based cancer therapeutics and gene regulation mechanisms.

RNA splicing and splice-switching therapeuticsAntisense oligonucleotide (ASO) drug designCancer molecular biology (liver and pancreatic cancer)Microbial metabolic engineeringBiosynthesis of plant natural products in bacteria

Publication output has been variable but with a notable increase in 2025, following a decade of low and intermittent annual output (mostly 0-2 papers per year).

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 1.8/year recently
2017: 1 publication17182019: 2 publications192020: 2 publications20212022: 2 publications222023: 2 publications232024: 1 publication242025: 4 publications42526
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Proceedings of the National Academy of Sciences×3
  • Scientific Reports×1
  • Cell Reports×1
  • Journal of Biological Chemistry×1
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By research-topic overlap
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  • Jing Peng

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  • Michela Garofalo

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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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