Emily K. Sims
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
236
Citations
4,640
Est. group size
~2
Recurring co-author estimate
Active years
32
Publishing since 1995
Emily K. Sims studies type 1 diabetes, a condition where the immune system attacks the insulin-producing beta cells of the pancreas. Her work focuses on identifying early biomarkers that predict who will develop the disease and on understanding how beta cells respond to inflammation and communicate with immune cells. This includes tracking molecules like proinsulin, C-peptide, and extracellular vesicles (tiny particles cells use to send signals) to improve early detection and inform prevention trials.
Publication activity has grown steadily over the past decade, rising from around 8 per year in 2017 to over 40 in 2025.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through June 2028 — about 2 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Indiana Medical Scientist/Engineer Training Program
Implications of Changes in Islet Exosomal Cargo in Type 1 Diabetes
Beta cell extracellular vesicles in health and disease
2 earlier awards
- NIH R03DK117253Dec 2018 – Nov 2021 · $205k awarded
Defining the Generation and Cargo of Extracellular Vesicles During the Evolution of Type 1 Diabetes
- NIH K08DK103983Sep 2014 – Jul 2020 · $159k awarded
Beta cell Derived miR-21 as an Intrinsic Protective Response and Biomarker in Type 1 Diabetes
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~11 · 8% small-team papers (≤3 authors) · across 53 venues
- Multi-omics data compendium of pancreatic islet and β cell responses to pro-inflammatory cytokines
Research Square · 2026
- Assessing extracellular vesicle proteins as predictive biomarkers for developing type 1 diabetes
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Accounting for age-related increases in HbA1c more accurately quantifies risk of Type 1 Diabetes progression in islet autoantibody-positive adults
medRxiv · 2026
- Going From Stage 2 to Stage 3 Type 1 Diabetes—Does Not Matter How You Got Here
Diabetes Care · 2026
- Carbamylome analysis reveals regulatory roles for lysine carbamylation in β-cell glycolytic and insulin-processing enzymes
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- C-Peptide Provides Critical Contextual Insight Into Elevated Glucose Values During Progression to Type 1 Diabetes
Diabetes Care · 2026
- IA-2A positivity increases risk of progression within and across established stages of type 1 diabetes
Diabetologia · 2025
- Autoimmune diabetes and targets for immunomodulation
Seminars in Immunology · 2025
- Reflecting on a Year at the Helm of Diabetes Care.
UNC Libraries · 2025
- Proinflammatory stress activates neutral sphingomyelinase 2 based generation of a ceramide-enriched β-cell EV subpopulation
2025
- Proinflammatory stress activates neutral sphingomyelinase 2 based generation of a ceramide-enriched β-cell EV subpopulation
2025
- 715-P: A Novel Approach for Assessing Treatment Failure vs. Success at Fixed Time Intervals in T1D Prevention Trials
Diabetes · 2025
- Baseline Insulin Secretion Determines Response to Abatacept in Stage 1 Type 1 Diabetes
Diabetes · 2025
- Associations of CGM Metrics With Stimulated C-Peptide Measures in Youth With Recent-Onset Type 1 Diabetes
Diabetes Care · 2025
- An Antibody Cocktail-Based Immunoaffinity-LC-MS Method Enabled Ultra-Sensitive and Robust Quantification of Circulating Proinsulin Proteoforms and C-Peptide
Analytical Chemistry · 2025
- Diabetes×53
- Diabetes Care×19
- Communications Medicine×16
- Diabetologia×12
- PMC×12
- Zeb Saeed
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jamie L. Felton
Biochemistry, Genetics and Molecular Biology · Indiana University
- Heba M. Ismail
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jennifer Skidmore
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Sarah J. Richardson
Biochemistry, Genetics and Molecular Biology · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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