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Elizabeth M. Topp

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1970
Protein purification and stabilityMonoclonal and Polyclonal Antibodies ResearchDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsMass Spectrometry Techniques and Applications

Publications

150

Citations

5,807

Est. group size

—

Recurring co-author estimate

Active years

57

Publishing since 1970

Research summary
AI-generated

Elizabeth M. Topp studies how protein and RNA-based drugs (like antibodies, therapeutic proteins, and mRNA) behave and degrade in different storage forms, such as freeze-dried or spray-dried solids and solutions. Her work uses techniques like hydrogen-deuterium exchange mass spectrometry to understand and improve the stability of these biologic drug formulations, which is important for developing effective and long-lasting medicines. This research sits at the intersection of pharmaceutical science, biochemistry, and analytical chemistry.

Protein and peptide drug stabilityFreeze-drying and spray-drying of biologicsHydrogen-deuterium exchange mass spectrometryProtein aggregation and fibrillationmRNA and RNA-based therapeutics

Publication output peaked around 2018-2020 and has since slowed, with fewer papers per year in the most recent five years compared to the prior period.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 1.8/year recently
2017: 3 publications172018: 6 publications182019: 7 publications7192020: 5 publications202021: 4 publications212022: 2 publications222023: 1 publication232024: 3 publications242025: 1 publication252026: 2 publications26
Recent publications
Publishes in
  • Molecular Pharmaceutics×15
  • Journal of Pharmaceutical Sciences×5
  • Pharmaceutical Research×5
  • International Journal of Pharmaceutics×4
  • Biophysical Journal×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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