LabCompass

Dyann M. Segvich

Medicine · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2008Rising activity
Glycogen Storage Diseases and MyoclonusGenetics and Neurodevelopmental DisordersBone health and osteoporosis researchLysosomal Storage Disorders ResearchAdipose Tissue and Metabolism

Publications

48

Citations

1,047

Est. group size

—

Recurring co-author estimate

Active years

19

Publishing since 2008

Research summary
AI-generated

Dyann M. Segvich studies how the body's sugar-storage molecule, glycogen, is built and broken down, with a particular focus on Lafora disease, a rare inherited disorder caused by abnormal glycogen buildup in brain cells. Her work spans basic biochemistry of glycogen-related enzymes (like glycogen synthase and the laforin/malin proteins) to early-stage drug and antibody-based approaches aimed at treating or detecting this glycogen buildup. This research is relevant to students interested in metabolic biochemistry, rare genetic diseases, and translational approaches to enzyme-targeted therapies.

Glycogen metabolism and storageLafora disease and glycogen-related neurological disordersEnzyme biochemistry (glycogen synthase, laforin, malin)Small-molecule and antibody-based therapeutic developmentBrain metabolism and protein glycosylation

Publication output has been variable but shows a marked increase in recent years, rising from just 1 publication in 2021-2022 to 5-7 per year in 2023-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.4/year recently
2017: 4 publications17182019: 3 publications192020: 3 publications202021: 1 publication212022: 1 publication222023: 5 publications232024: 7 publications7242025: 6 publications252026: 3 publications26
Recent publications
Publishes in
  • Bone×5
  • SSRN Electronic Journal×5
  • Journal of Biological Chemistry×3
  • Bone Reports×3
  • Cell Metabolism×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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