Diana D. Kang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
35
Citations
1,501
Est. group size
~12
Recurring co-author estimate
Active years
23
Publishing since 2004
Diana D. Kang's research focuses on designing lipid nanoparticles (LNPs) — tiny fat-based particles — to deliver mRNA and other RNA-based therapies to specific tissues, especially the brain and central nervous system, but also lungs, tumors, and wounds. This work spans applications like crossing the blood-brain barrier for neurological disease treatment, cancer immunotherapy, antiviral therapies, and wound healing. Prospective students would work on chemistry and materials engineering problems related to drug delivery, combined with molecular biology techniques for testing these therapies in cells and animals.
Publication output has grown substantially over the last decade, rising from no publications before 2020 to a peak of 13 in 2025, indicating an accelerating and increasingly active research output.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- mRNA-based MRI contrast agent for precise diagnosis of glioma and pseudoprogression
Cell Biomaterials · 2026
- Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system
Nature Materials · 2025
- Lipid nanoparticles for mRNA delivery in brain via systemic administration
Science Advances · 2025
- Lipid Nanoparticles Enhance mRNA Delivery to the Central Nervous System Upon Intrathecal Injection
Advanced Materials · 2025
- LNP-RNA-mediated antigen presentation leverages SARS-CoV-2-specific immunity for cancer treatment
Nature Communications · 2025
- Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level
Nature Biomedical Engineering · 2025
- Furan-Derived Lipid Nanoparticles for Transporting mRNA to the Central Nervous System
Journal of the American Chemical Society · 2025
- Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia
Nature Biotechnology · 2025
- Enhancing antitumor immunity through chemotherapeutic-derived lipid nanoparticle-induced immunogenic cell death and CD40L/Flt3L mRNA-mediated dendritic cell activation
Journal of Controlled Release · 2025
- An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo
Science Translational Medicine · 2025
- SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo
Advanced Science · 2025
- Aminophosphonate-Derived lipid nanoparticles enable circular RNA delivery for functional recovery after spinal cord injury
Materials Today · 2025
- Author Correction: Intravenous administration of blood–brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system
Nature Biotechnology · 2025
- Rational design and applications of piperazine and cyclohexane ionizable lipids for PKU and SSADH deficiency
Molecular Therapy — Nucleic Acids · 2025
- LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing
Nature Communications · 2024
- Nature Communications×3
- Advanced Materials×3
- Nature Biotechnology×3
- Journal of Controlled Release×2
- Advanced Drug Delivery Reviews×2
- Yonger Xue
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Shi Du
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Huan Zhang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Yizhou Dong
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Yuebao Zhang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile