Publications
291
Citations
13,569
Est. group size
~3
Recurring co-author estimate
Active years
44
Publishing since 1983
David Giedroc studies how bacteria manage metal ions such as zinc inside their cells, including how they sense metals, move them around, and use metal-containing proteins to survive stress. Much of the work focuses on disease-causing bacteria like Acinetobacter baumannii and Streptococcus pneumoniae, examining the molecular machinery for metal handling, cell wall building, and gene regulation. The research combines biochemistry, biophysics, and structural analysis of proteins and their interactions with DNA and metals.
Publication output was higher in the late 2010s (peaking around 2019) and has settled to a steady pace of roughly 7-8 papers per year in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through February 2031 — about 4 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Transition Metal Homeostasis and Reactive Sulfur Chemistry in Bacterial Pathogens
Graduate Training Program in Quantitative and Chemical Biology at Indiana University Bloomington
7 earlier awards
- NIH S10OD032431Jun 2023 – Nov 2025 · $2.0M awarded
Acquisition of an 800 MHz hybrid solution-/solid-state NMR spectrometer
- NIH T32GM109825Jul 2014 – Jun 2019 · $282k awarded
Graduate Program in Quantitative and Chemical Biology at Indiana University Bloom
- NIH R01GM042569Apr 1991 – Apr 2016 · $396k awarded
Structure and Mechanism of Metalloregulatory Proteins
- NIH R01GM097225Apr 2011 – Mar 2016 · $267k awarded
New mechanisms of sulfur sensing and trafficking in Staphylococcus aureus.
- NSF 1048613Dec 2010 – Nov 2014 · $320k awarded
Acquisition of a Modern X-ray Powder Diffractometer to Support Researchers and Educators
- NIH R01AI067416Jan 2008 – Dec 2013 · $355k awarded
Novel RNA Structures in Coronavirus Replication
- NSF 9217413Sep 1993 – Jul 1997 · $275k awarded
Acquisition of a 500 MHz NMR Spectrometer
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~6 · 27% small-team papers (≤3 authors) · across 51 venues
- “Self-gapping” by a C-terminal domain arginine finger regulates GTP hydrolysis in bacterial zinc metallochaperones
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Acinetobacter baumannii MigC C-terminal domain core
Biological Magnetic Resonance Bank · 2026
- Self-activation by a C-terminal domain arginine finger regulates GTP hydrolysis in bacterial zinc metallochaperones
Proceedings of the National Academy of Sciences · 2026
- In vitro evolution of DNA operators enables multivalency protein−DNA interactions: towards programmable transcription factor regulation
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Evolution of allostery without shape shifting: Internal dynamics drives functional diversification of a transcriptional repressor superfamily
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- CH•••S hydrogen bonds drive molecular recognition of ergothioneine by the microbial transporter
Science Advances · 2026
- Monitoring UDP-MurNAc (UM)-Stem Peptide Intermediates from the Cellular and Recombinant Acinetobacter baumannii MurCDEF Pathway
ACS Infectious Diseases · 2026
- GTP hydrolysis-powered zinc metallochaperones as molecular switches
Current Opinion in Chemical Biology · 2026
- The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii
PLoS Pathogens · 2025
- Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics
ACS Chemical Biology · 2025
- Analysis of genetic requirements and nutrient availability for Staphylococcus aureus growth in cystic fibrosis sputum
mBio · 2025
- Exploring metalloproteome remodeling in calprotectin-stressed Acinetobacter baumannii using chemoproteomics
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii
Open MIND · 2025
- The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii
University of Chicago · 2025
- CH•••S hydrogen bonds drive molecular recognition of ergothioneine by the microbial transporter
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- bioRxiv (Cold Spring Harbor Laboratory)×15
- Biological Magnetic Resonance Bank×5
- Journal of Biological Chemistry×4
- Proceedings of the National Academy of Sciences×4
- Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature×4
- Katherine A. Edmonds
Nursing · Indiana University
- Amanda Bird
Nursing · The Ohio State University
- Mark L. Failla
Nursing · The Ohio State University
- Fred Askari
Nursing · University of Michigan
- Melissa L. Zastrow
Nursing · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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