David B. Heisler

David B. Heisler's research examines how cells defend themselves against viral and bacterial infections, including how cholesterol and lipid metabolism restrict microbial invasion, and how RNA structures like G-quadruplexes regulate gene expression. Recent work has also explored antiviral pathways that operate independently of interferons (a common immune-signaling system) and are targeted by poxvirus proteins. This work spans molecular virology, structural RNA biology, and cell biology using both experimental and bioinformatic approaches.

Publication output has grown over the past decade, rising from sporadic single papers in the late 2010s to a more consistent 3-5 publications per year since 2023.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026