LabCompass

Daniel P. Flaherty

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2007
Enzyme function and inhibitionPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and Catalytic ReactionsUbiquitin and proteasome pathwaysAntimicrobial Resistance in Staphylococcus

Publications

112

Citations

1,633

Est. group size

~15

Recurring co-author estimate

Active years

20

Publishing since 2007

Research summary
AI-generated

Daniel P. Flaherty's research focuses on developing small-molecule drugs, particularly enzyme inhibitors, to combat drug-resistant bacterial infections such as gonorrhea and vancomycin-resistant enterococci, with carbonic anhydrase (an enzyme involved in regulating acidity in cells) as a frequent drug target. The lab also works on related biochemical targets including deubiquitinating enzymes (proteins that remove regulatory tags from other proteins) and adenylyl cyclase for non-opioid pain treatment, using medicinal chemistry and structure-activity studies to design and optimize new compounds.

Antibiotic drug discovery for resistant bacteriaCarbonic anhydrase inhibitor designMedicinal chemistry and structure-activity relationshipsEnzyme-targeted therapeutics (deubiquitinases, adenylyl cyclase)Non-opioid pain drug development

Publication output has grown substantially over the last decade, rising from a handful of papers per year in 2017-2019 to a sustained higher rate of roughly 8-14 papers annually from 2021 onward.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 9.0/year recently
2017: 2 publications172018: 4 publications182019: 4 publications192020: 5 publications202021: 12 publications212022: 9 publications222023: 6 publications232024: 14 publications14242025: 8 publications252026: 8 publications26
Recent publications
Publishes in
  • Journal of Medicinal Chemistry×8
  • Journal of Enzyme Inhibition and Medicinal Chemistry×7
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Antibiotics×3
  • ACS Infectious Diseases×2
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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