Clayton Cuddington
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
25
Citations
256
Est. group size
~5
Recurring co-author estimate
Active years
8
Publishing since 2019
This researcher develops and tests polymerized and modified forms of hemoglobin—the oxygen-carrying protein in blood—as potential substitutes for donated blood in emergencies like hemorrhagic shock and trauma. Work spans engineering these blood substitutes, characterizing their physical and chemical properties, and testing their safety and effectiveness in animal models of blood loss, brain injury, and metabolic disease. The research combines biochemistry, bioengineering, and physiology to address practical challenges in resuscitation medicine.
Publication output rose sharply around 2020 and has continued at a moderate, somewhat variable pace through 2024, following a gap in 2017-2018.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Novel high molecular weight polymerized hemoglobin in a non-obese model of cardiovascular and metabolic dysfunction
Biomedicine & Pharmacotherapy · 2024
- Polymerized human hemoglobin with low and high oxygen affinity in trauma models
Translational research · 2023
- Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock
Scientific Reports · 2022
- Scalable production and complete biophysical characterization of poly(ethylene glycol) surface conjugated liposome encapsulated hemoglobin (PEG-LEH)
PLoS ONE · 2022
- Safety profile and efficacy of low and high oxygen affinity polymerized human hemoglobin in trauma model
The FASEB Journal · 2022
- Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin
Scientific Reports · 2021
- Biophysical properties of tense quaternary state polymerized human hemoglobins bracketed between 500 <scp>kDa</scp> and 0.2 μm in size
Biotechnology Progress · 2021
- Human polymerized hemoglobin as an alternative to blood in resuscitation from hemorrhagic shock
The FASEB Journal · 2021
- Author response for "Biophysical properties of tense quaternary state polymerized human hemoglobins bracketed between 500 kDa and 0.2 μm in size"
2021
- Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation
iScience · 2020
- Next‐generation polymerized human hemoglobins in hepatic bioreactor simulations
Biotechnology Progress · 2020
- Resuscitation from Hemorrhagic Shock after Traumatic Brain Injury with Polymerized Hemoglobin
The FASEB Journal · 2020
- Cardiovascular effects of polymerized hemoglobin in a dyslipidemia model
The FASEB Journal · 2020
- Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier
Bioconjugate Chemistry · 2019
- Author response for "Use of Next‐Generation Polymerized Human Hemoglobins in Hepatic Bioreactor Simulations"
2019
- The FASEB Journal×4
- ASAIO Journal×3
- Scientific Reports×2
- Biotechnology Progress×2
- Biotechnology and Bioengineering×2
- Savannah R. Wolfe
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Quintin O’Boyle
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Andre F. Palmer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Ivan S. Pires
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Chintan Savla
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile