Clark D. Wells
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
65
Citations
3,267
Est. group size
—
Recurring co-author estimate
Active years
29
Publishing since 1997
Clark D. Wells studies how cells send and receive growth signals, focusing on the Hippo pathway and its central proteins YAP1/TAZ, along with the adaptor protein angiomotin (AMOT) that helps control cell proliferation. This work connects basic cell signaling to disease contexts such as cancer, glioblastoma, kidney cyst formation, and muscle wasting (cachexia). Some projects also involve screening chemical compounds and characterizing protein structure to identify potential drug targets.
Publication activity has been relatively low and steady over the past decade (roughly one to three papers most years), with a peak of five in 2023.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
No award with a current end date on record.
1 earlier award
- NIH R01CA151765Jun 2011 – Apr 2018 · $312k awarded
Regulation of Mammary Cell Proliferation by Apical Polarity Proteins
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~9 · 5% small-team papers (≤3 authors) · across 13 venues
- Deciphering the unique mechanism whereby bis-sulfonamido-2-phenylbenzoxazole (PBZ) GroEL/ES inhibitors modulate chaperonin ATPase and client protein folding functions.
ChemRxiv · 2025
- Hepatic Yap1 activates systemic catabolism and muscle loss during organ repair: evidence for a liver-derived common mechanism with cancer cachexia
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Data from The Adaptor Protein AMOT Promotes the Proliferation of Mammary Epithelial Cells via the Prolonged Activation of the Extracellular Signal-Regulated Kinases
2023
- Data from The Adaptor Protein AMOT Promotes the Proliferation of Mammary Epithelial Cells via the Prolonged Activation of the Extracellular Signal-Regulated Kinases
2023
- Supplementary Methods, Figures 1-6 from The Adaptor Protein AMOT Promotes the Proliferation of Mammary Epithelial Cells via the Prolonged Activation of the Extracellular Signal-Regulated Kinases
2023
- Role of <scp>CD14</scp> in human disease
Immunology · 2023
- Supplementary Methods, Figures 1-6 from The Adaptor Protein AMOT Promotes the Proliferation of Mammary Epithelial Cells via the Prolonged Activation of the Extracellular Signal-Regulated Kinases
2023
- Reconstitution of renal cyst formation in 3D culture reveals a role for AMOT and Yap1 in determining cyst size
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- The RGS-RhoGEFs control the amplitude of YAP1 activation by serum
Scientific Reports · 2021
- Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data
Author eBooks · 2020
- Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data
ACS Chemical Biology · 2020
- Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association
ACS Omega · 2019
- Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association
PMC · 2019
- regSNPs-splicing: a tool for prioritizing synonymous single-nucleotide substitution
Human Genetics · 2017
- Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist
PMC · 2017
- PMC×2
- IUScholarWorks (Indiana University)×2
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Cell chemical biology×1
- Immunology×1
- Shuling Fan
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Aktan Alpsoy
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Ben Margolis
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Benjamin D. Ferguson
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Emily M. King
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
Claim or correct this profile