Publications
104
Citations
7,929
Est. group size
—
Recurring co-author estimate
Active years
38
Publishing since 1988
This researcher studies proteins embedded in cell membranes that move drugs across cell barriers or process other proteins, including the transporters P-glycoprotein and ABCG2 (which pump drugs out of cells and affect drug resistance in cancer and drug penetration into the brain) and enzymes like Ste24/ZMPSTE24 (which cut and chemically modify precursor proteins, relevant to aging-related diseases). The work combines biochemistry, peptide chemistry, and enzyme assays to understand how these proteins recognize and act on their substrates, with implications for drug design and disease mechanisms.
Publication output has fluctuated over the last decade, with a peak in 2019 and 2023 and a lower, uneven pace in other years, averaging under two publications per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Upstream Proteolysis by Ste24 does not Require a C-Terminal Methyl Ester as Revealed Using 33-Residue a-Factor Precursor Peptide Substrates Synthesized via Epimerization-Free Methods
International Journal of Peptide Research and Therapeutics · 2025
- Upstream proteolysis by Ste24 does not require a C-terminal methyl ester as revealed using 33-residue a-factor precursor peptide substrates synthesized via epimerization-free methods
Research Square · 2024
- Supplementary Figure 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Data from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Supplementary Table 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Supplementary Table 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Data from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Supplementary Figure 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
2023
- Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation
ACS Chemical Biology · 2022
- The roles of the human ATP-binding cassette transporters P-glycoprotein and ABCG2 in multidrug resistance in cancer and at endogenous sites: future opportunities for structure-based drug design of inhibitors
Cancer Drug Resistance · 2021
- Methyltransferase-like 21c methylates and stabilizes the heat shock protein Hspa8 in type I myofibers in mice
Journal of Biological Chemistry · 2019
- Methyltransferase‐like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
The FASEB Journal · 2019
- A Quantitative FRET Assay for the Upstream Cleavage Activity of the Integral Membrane Proteases Human ZMPSTE24 and Yeast Ste24
Methods in molecular biology · 2019
- Elucidation of the Substrate Binding Site of the Yeast Zinc Metalloprotease, Ste24
The FASEB Journal · 2019
- Dimerization of Yeast Ste14 Isoprenylcysteine Carboxyl Methyltransferase
The FASEB Journal · 2019
- The FASEB Journal×3
- Proceedings of the National Academy of Sciences×1
- Cancer Drug Resistance×1
- Disease Models & Mechanisms×1
- Journal of Biological Chemistry×1
- Deanna L. Kroetz
Medicine · The Ohio State University
- Alice A. Gibson
Medicine · The Ohio State University
- Brian Middleton
Medicine · Indiana University
- Alex Sparreboom
Medicine · The Ohio State University
- David R. Foster
Medicine · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile