Chi Zhang
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
72
Citations
1,731
Est. group size
~19
Recurring co-author estimate
Active years
16
Publishing since 2011
Chi Zhang's research develops and applies advanced optical microscopy and imaging methods, especially label-free chemical imaging techniques like coherent/stimulated Raman scattering microscopy, to study cellular and tissue biology. Applications span metabolic profiling of lipids and mitochondria, drug and antisense oligonucleotide delivery, vacuolar membrane trafficking, and disease-related processes in the brain, liver, and microbes. The work combines biophysical imaging tool development with questions in cell biology, pharmacology, and neuroscience.
Publication output has grown substantially over the last decade, rising from a few papers per year around 2017-2018 to a peak of 19 in 2025, indicating an increasingly active and productive research program.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Optimizing stereotaxic injection strategy for AAV-mediated corticospinal tract tracing in mice
Journal of Neuroscience Methods · 2026
- Neuroprotective properties of extra virgin olive oil polyphenols in Alzheimer’s disease: a multi-target mechanistic review
Frontiers in Nutrition · 2025
- Detecting early-stage apoptosis using stimulated Raman scattering microscopy
2025
- Vacuolar Phosphatidylinositol 3,4,5-trisphosphate controls fusion through binding Vam7, and membrane microdomain assembly
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- High-throughput single-cell sorting by stimulated Raman-activated cell ejection
Science Advances · 2024
- Large field-of-view metabolic profiling of murine brain tissue following morphine incubation using label-free multiphoton microscopy
Journal of Neuroscience Methods · 2024
- Coherent Raman scattering microscopy of lipid droplets in cells and tissues
Journal of Raman Spectroscopy · 2023
- Pathological bile acid concentrations in chronic cholestasis cause adipose mitochondrial defects
JHEP Reports · 2023
- Chemical-imaging-guided optical manipulation of biomolecules
Frontiers in Chemistry · 2023
- A multimodal nonlinear optical microscopy study of the responses of <i>Pseudomonas aeruginosa</i> to blue light and antibiotic treatment
Journal of Biophotonics · 2023
- High throughput analysis of vacuolar acidification
Analytical Biochemistry · 2022
- Differential uptake of antisense oligonucleotides in mouse hepatocytes and macrophages revealed by simultaneous 2P-fluorescence and coherent Raman imaging
2022
- High throughput analysis of vacuolar acidification
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- Coherent Raman scattering microscopy for chemical imaging of biological systems
Journal of Physics Photonics · 2021
- Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging
Nucleic Acid Therapeutics · 2021
- bioRxiv (Cold Spring Harbor Laboratory)×10
- Analytical Chemistry×5
- Nature Communications×3
- Science Advances×2
- Traffic×2
- Gil A. Gonzalez
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Gregory Eakins
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Minghe Li
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Charles L. Hitchcock
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Aleksandr Razumtcev
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile