Publications
81
Citations
1,882
Est. group size
—
Recurring co-author estimate
Active years
38
Publishing since 1988
Chafiq Hamdouchi works in medicinal and synthetic chemistry, focusing on designing and making drug-like small molecules. Much of the recent work centers on GPR40 (also called FFAR1), a receptor targeted for treating type 2 diabetes, including the discovery and early development of candidate compounds. The research combines organic synthesis with understanding how molecules bind to and activate biological targets.
Publication activity has been low and intermittent over the past decade, averaging under one indexed paper per year.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through February 2027 — about under a year of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Development of BBB-permeable SUMO1 small molecule degraders for glioblastoma therapy.
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~26 · 0% small-team papers (≤3 authors) · across 4 venues
- Structural basis for GPR40 allosteric agonism and incretin stimulation
Nature Communications · 2018
- Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus
Journal of Medicinal Chemistry · 2017
- The Role of GPR40 (FFAR1) in Pharmacological vs Physiological Control of Incretin Secretion
The FASEB Journal · 2017
- The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470)
Journal of Medicinal Chemistry · 2016
- A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes
Pharmacology Research & Perspectives · 2016
- 2型糖尿病治療のための強力な選択的GPR40作動薬(LY2881835,LY2922083,LY2922470)の発見,前臨床及び初期臨床開発
Journal of Medicinal Chemistry · 2016
- Journal of Medicinal Chemistry×3
- Nature Communications×1
- Science Translational Medicine×1
- Pharmacological Research×1
- Pharmacology Research & Perspectives×1
- Jie Jack Li
Chemistry · University of Michigan
- Linzhou Wang
Chemistry · The Ohio State University
- Jakka Raghavaiah
Chemistry · Purdue University West Lafayette
- Christian Jacobsen
Chemistry · University of Michigan
- P. Veeraraghavan Ramachandran
Chemistry · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 27, 2026.
Claim or correct this profile