LabCompass

Casey J. Krusemark

Chemistry · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2006
Click Chemistry and ApplicationsChemical Synthesis and AnalysisMonoclonal and Polyclonal Antibodies ResearchEpigenetics and DNA MethylationAdvanced biosensing and bioanalysis techniques

Publications

52

Citations

984

Est. group size

~6

Recurring co-author estimate

Active years

21

Publishing since 2006

Research summary
AI-generated

Casey J. Krusemark's research focuses on chemical methods for discovering molecules that bind to specific proteins, particularly using large collections of DNA-tagged compounds called DNA-encoded libraries (DELs). This work involves designing new chemical reactions to attach molecules to proteins (covalent inhibitors), developing assays to test many candidate molecules at once, and applying these tools to targets like cancer-related proteins and enzymes. Students in this group would likely gain experience in organic synthesis, chemical biology assay design, and DNA-based screening technologies.

DNA-encoded chemical librariesCovalent protein inhibitorsChemical biology assay developmentEpigenetic protein targets (e.g., Polycomb proteins)Enzyme-linked and proximity-based labeling methods

Publication output has fluctuated but shown an overall increase over the last decade, with a notable peak in 2023 and continued activity through 2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.2/year recently
2017: 1 publication172018: 1 publication182019: 5 publications192020: 1 publication202021: 6 publications212022: 4 publications222023: 10 publications10232024: 2 publications242025: 1 publication252026: 4 publications26
Recent publications
Publishes in
  • Angewandte Chemie International Edition×4
  • Angewandte Chemie×4
  • ChemRxiv×4
  • Journal of the American Chemical Society×1
  • Cancer Research×1
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By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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