Carol Beth Post
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
130
Citations
13,979
Est. group size
—
Recurring co-author estimate
Active years
59
Publishing since 1968
Carol Beth Post studies the three-dimensional shapes (structures) and movements (dynamics) of proteins, with particular focus on kinases—enzymes that regulate cell signaling by adding phosphate groups to other proteins. Her work combines computational simulations (like molecular dynamics) with experimental methods such as NMR spectroscopy to understand how proteins change shape to become active or bind other molecules. This research helps explain how signaling proteins like Src and Syk kinases are switched on and off, which is relevant to understanding cellular communication and disease processes.
Publication output has been steady but modest over the last decade, with some fluctuation (a gap in 2021) and a slight recent uptick between 2023 and 2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- An electrostatic network with strong connectivity is a phospho-sensor for regulating affinity of Syk–receptor association
Proceedings of the National Academy of Sciences · 2025
- Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases
Nature Communications · 2024
- Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Biomolecular dynamics in the 21st century
Biochimica et Biophysica Acta (BBA) - General Subjects · 2023
- Computation of conformational transitions and activation of Src tyrosine kinase
Biophysical Journal · 2023
- All-atom adaptively biased path optimization of Src kinase conformational inactivation: Switched electrostatic network in the concerted motion of αC helix and the activation loop
The Journal of Chemical Physics · 2020
- Substrate binding to Src: A new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics
Protein Science · 2019
- Protein Conformational Transitions from All-Atom Adaptively Biased Path Optimization
Journal of Chemical Theory and Computation · 2018
- Editorial overview: Theory & computation
Current Opinion in Structural Biology · 2017
- A minimization principle for transition paths of maximum flux for collective variables
Theoretical Chemistry Accounts · 2016
- The Journal of Physical Chemistry B×2
- ChemBioChem×2
- Protein Science×2
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Biophysical Journal×2
- Tsukasa Nakamura
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Chiwook Park
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Jacob Verburgt
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Andrzej Kloczkowski
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Charles Christoffer
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile