LabCompass

Bryon Drown

Chemistry · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2012
Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry StudiesProtein purification and stabilityMicrofluidic and Capillary Electrophoresis Applications

Publications

82

Citations

1,495

Est. group size

—

Recurring co-author estimate

Active years

15

Publishing since 2012

Research summary
AI-generated

Bryon Drown works in analytical and chemical biology, using mass spectrometry-based tools to study proteins in their full complexity, including modifications and variant forms (called proteoforms). Their work includes developing software and lab protocols for top-down proteomics (analyzing whole proteins rather than digested fragments), studying enzymes involved in protein degradation (deubiquitinases), and developing assays to find drug candidates such as SARS-CoV-2 macrodomain inhibitors. This research could interest students wanting to work at the interface of chemistry, mass spectrometry instrumentation, and biological questions like disease-related protein modifications.

Top-down proteomics and mass spectrometryProtein modifications and proteoformsDeubiquitinase enzyme chemistry and covalent probesBioinformatics tools for mass spectrometry data analysisDrug discovery assay development

Publication output rose sharply from 2017 to a peak around 2020-2021, then declined and has remained lower but steady from 2023 onward.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.6/year recently
2017: 1 publication172018: 5 publications182019: 1 publication192020: 17 publications202021: 22 publications22212022: 14 publications222023: 4 publications232024: 4 publications242025: 3 publications252026: 3 publications26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×4
  • Science Advances×2
  • Journal of Biological Chemistry×2
  • Cell chemical biology×2
  • ACS Chemical Biology×2
Similar researchers
By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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