LabCompass

Bruce T. Lamb

Medicine · Indiana University

OpenAlex ORCID
Established · publishing since 1988
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysNeurological Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Publications

286

Citations

17,129

Est. group size

~2

Recurring co-author estimate

Active years

39

Publishing since 1988

Research summary
AI-generated

Bruce T. Lamb studies the biological mechanisms of Alzheimer's disease and related dementias, with a focus on how genetic risk factors (such as APOE4, TREM2, and PLCG2) and environmental influences drive brain changes. Much of the work involves developing and characterizing mouse models and stem-cell-derived cells to understand the roles of immune cells (microglia), inflammation, and other cell types in disease progression.

Alzheimer's disease mechanismsGenetic risk factors and mouse modelsNeuroinflammation and microgliaLate-onset dementia and environmental factorsRetinal and glial cell dysfunction

Publication activity has been steady with year-to-year fluctuation over the past decade, averaging around 15 papers per year in the most recent five years.

Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026

Funding
Public award records

Current awards run through June 2030 — about 4 years of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.

  • ActiveNIH U54AG090792through Jun 2030 · $3.3M awarded

    Microphysiological systems to Advance Precision medicine for Alzheimer's Disease and Related Dementias (MAP-AD)

  • ActiveNIH U01AG088021through Dec 2029 · $2.2M awarded

    Optimization of SHIP1 Inhibitors for the Treatment of Alzheimer's Disease

  • ActiveNIH U54AG065181through Nov 2029 · $8.3M awarded

    IUSM TREAT-AD Center

  • ActiveNIH U54AG054345through Aug 2027 · $634k awarded

    Administrative and Coordination Core

5 earlier awards
  • NIH R01AG069425Sep 2020 – Aug 2026 · $746k awarded

    Deciphering the role of CX3CR1 in Modulating Mechanisms of Amyloid driven Neurodegeneration in Alzheimer's Disease

  • NIH R01AG074566Sep 2021 – Aug 2026 · $754k awarded

    Impact of PLCG2 Alzheimer's Disease Risk Variants on Microglia Biology and Disease Pathogenesis

  • NIH T32AG071444May 2021 – Apr 2026 · $506k awarded

    Training Grant on Alzheimer's Disease and ADRD at Indiana University

  • NIH RF1AG069425Sep 2020 – Aug 2024 · $3.1M awarded

    Deciphering the role of CX3CR1 in Modulating Mechanisms of Amyloid driven Neurodegeneration in Alzheimer's Disease

  • NIH RF1AG074566Sep 2021 – Aug 2024 · $2.3M awarded

    Impact of PLCG2 Alzheimer's Disease Risk Variants on Microglia Biology and Disease Pathogenesis

Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.

In context
Among 5,073 established Medicine PIs within our index
Citations: 17,129cohort median 2,525
h-index: 63cohort median 24
Publications / year (recent): 15.4cohort median 4.8

Typically publishes in teams of ~12 · 4% small-team papers (≤3 authors) · across 43 venues

Publication cadence
Publications per year over the last 10 years — averaging 15.4/year recently
2017: 12 publications172018: 27 publications182019: 18 publications192020: 34 publications34202021: 10 publications212022: 25 publications222023: 24 publications232024: 17 publications242025: 8 publications252026: 3 publications26
Collaborators per year
Distinct co-authors at Indiana University each year — a rough indication of whether the group around this researcher has been growing or contracting. An estimate from co-authorship, not a roster: collaborators are not necessarily lab members, and recent years can be under-counted while indexing catches up.
2017: 0 collaborators at the same institution2018: 2 collaborators at the same institution2019: 0 collaborators at the same institution2020: 8 collaborators at the same institution2021: 4 collaborators at the same institution2022: 16 collaborators at the same institution2023: 19 collaborators at the same institution2024: 0 collaborators at the same institution2025: 1 collaborator at the same institution1719212325
Recent publications
Publishes in
  • Alzheimer s & Dementia×79
  • bioRxiv (Cold Spring Harbor Laboratory)×14
  • Figshare×10
  • Alzheimer s & Dementia Translational Research & Clinical Interventions×7
  • Molecular Neurodegeneration×5
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Sep 1, 2026.

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