Brittany Sandoval
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
18
Citations
618
Est. group size
—
Recurring co-author estimate
Active years
9
Publishing since 2018
Brittany Sandoval's research focuses on how proteins are targeted for degradation inside cells, particularly through molecular glue compounds and ubiquitin ligases (enzymes that mark proteins for destruction). This work has applications in cancer biology, especially blood cancers like leukemia, where degrading specific proteins can kill cancer cells while sparing healthy ones. The research combines chemistry (designing degrader molecules) with molecular biology and genetics (understanding disease mechanisms in blood disorders).
Publication output was low and sporadic from 2017-2021 (0-1 papers/year) but increased notably starting in 2022-2023, suggesting a growing and more active research output in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Template-assisted covalent modification underlies activity of covalent molecular glues
Nature Chemical Biology · 2024
- Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues
European Journal of Medicinal Chemistry · 2024
- UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability
Molecular Cell · 2023
- PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy
Blood · 2023
- Synthesis of Poly(allyl glycidyl ether)-Derived Polyampholytes and Their Application to the Cryopreservation of Living Cells
Biomacromolecules · 2023
- Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Exploration of the Tunability of BRD4 Degradation by DCAF16 <i>Trans</i> -labelling Covalent Glues
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Abstract 3424: Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders
Cancer Research · 2023
- Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells
Journal of Clinical Investigation · 2022
- UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability
Blood · 2022
- Association of clonal hematopoiesis with chronic obstructive pulmonary disease
Blood · 2021
- A Prospective Study and Identification of Genomewide Association Markers of Familial Predisposition to Plasma Cell Dyscrasias
Blood · 2020
- Heat Shock Proteins As A Potential Tool To Protect Cells Integrity During Organ Cryopreservation
Cryobiology · 2019
- L89S Mutant of FeBMb Sperm Whale Myoglobin
2018
- Blood×4
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Cancer Research×2
- Nature Chemical Biology×1
- Molecular Cell×1
- Katiri Snyder
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Hannah M. Jacobs
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Bennet D. Elzey
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Emily Stahl
Medicine · The Ohio State University
- Krishan Kumar
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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