LabCompass

Brian R. Overholser

Medicine · Purdue University West Lafayette

Mid career · publishing since 2003

Publications

103

Citations

1,976

Est. group size

~4

Recurring co-author estimate

Active years

24

Publishing since 2003

Research summary
AI-generated

Brian R. Overholser's work focuses on how drugs are absorbed, processed, and eliminated by the body (pharmacokinetics), with particular attention to heart rhythm safety issues like QT interval prolongation, and to how genetic variation and vitamin D affect drug metabolism in organ transplant patients. Much of this research aims to inform safer, more individualized dosing of medications such as tacrolimus and mycophenolic acid used after kidney and liver transplants. This research sits at the intersection of clinical pharmacology, cardiology, and transplant medicine.

Pharmacokinetics and drug metabolismCardiac arrhythmia and QT interval safetyGenetic variation in drug-metabolizing enzymesTransplant medicine (kidney and liver)Personalized drug dosing

Publication output has fluctuated over the last decade with peaks around 2019-2020 and 2022, followed by somewhat lower but still ongoing output through 2025, averaging about 4 publications per year in the last 5 years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.0/year recently
172018: 3 publications182019: 8 publications8192020: 8 publications8202021: 4 publications212022: 8 publications8222023: 2 publications232024: 4 publications242025: 5 publications252026: 1 publication26
Publishes in
  • Circulation×6
  • Elsevier eBooks×4
  • PMC×4
  • Journal of the American College of Cardiology×4
  • Pharmacogenomics×3
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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