LabCompass

Aswathy Chandran

Medicine · Purdue University West Lafayette

OpenAlex ORCID
Early career · publishing since 2017Rising activity
Parkinson's Disease Mechanisms and TreatmentsAmyotrophic Lateral Sclerosis ResearchRNA regulation and diseaseAutophagy in Disease and TherapyNeurological disorders and treatments

Publications

14

Citations

181

Est. group size

~1

Recurring co-author estimate

Active years

9

Publishing since 2017

Research summary
AI-generated

Aswathy Chandran's research focuses on the molecular biology of Parkinson's disease, particularly how the protein alpha-synuclein misfolds, clumps together, and forms abnormal cellular structures called condensates. Recent work examines specific genetic mutations in alpha-synuclein found in patients, how other proteins like VAMP2 regulate this clumping process, and related mechanisms such as autophagy (a cell's waste-clearing system) and mitochondrial dysfunction in neurodegeneration. The work combines patient genetic data, lab-based protein studies, and computational (in silico) analysis.

Alpha-synuclein aggregation and phase separationParkinson's disease genetics and missense variantsAutophagy and protein quality control in neurodegenerationNeurotoxicity and cellular models of Parkinson's diseaseExosomal and mitochondrial mechanisms in neurodegenerative disease

Publication output has grown notably in recent years, rising from sporadic single papers earlier in the decade to multiple publications per year in 2023-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.0/year recently
2017: 1 publication17182019: 2 publications19202021: 1 publication21222023: 2 publications232024: 3 publications242025: 5 publications52526
Recent publications
Publishes in
  • medRxiv×2
  • bioRxiv (Cold Spring Harbor Laboratory)×2
  • Nature Cell Biology×1
  • Journal of Molecular Biology×1
  • Biology×1
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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