Anna M. Gutridge
Pharmacology, Toxicology and Pharmaceutics · Purdue University West Lafayette
Publications
21
Citations
305
Est. group size
~4
Recurring co-author estimate
Active years
9
Publishing since 2016
Anna M. Gutridge's research focuses on studying and chemically modifying opioid receptor-targeting compounds, many derived from natural plant alkaloids (such as those from kratom and akuamma plants), to understand how they interact with the body's opioid receptors. Her work explores potential therapies for conditions like alcohol use disorder, opioid overdose, and pain management, while aiming to reduce the harmful side effects typically associated with opioid drugs.
Publication output rose to a peak in 2021 (8 publications) after low activity in 2017-2018, then settled into a steady but modest pace of about 2 publications per year through 2024.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Discovery of Potent Kappa Opioid Receptor Agonists Derived from Akuammicine
Journal of Medicinal Chemistry · 2024
- Discovery of Potent Kappa Opioid Receptor Agonists Derived from Akuammicine
ChemRxiv · 2024
- Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor
Journal of Medicinal Chemistry · 2023
- Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor
ChemRxiv · 2023
- Sex- and β-arrestin-dependent effects of kappa opioid receptor-mediated ethanol consumption
Pharmacology Biochemistry and Behavior · 2022
- Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor
ChemRxiv · 2022
- A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects
Journal of Medicinal Chemistry · 2021
- Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder
Frontiers in Pharmacology · 2021
- Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities
Molecules · 2021
- Engineering Quick- and Long-acting Naloxone Delivery Systems for Treating Opioid Overdose
Pharmaceutical Research · 2021
- A novel mitragynine analog with low efficacy mu-opioid receptor agonism displays antinociception with attenuated adverse effects
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Pharmacological Characterization of Synthetic Kratom Alkaloids for Improved Alcohol Use Disorder Therapeutics
The FASEB Journal · 2021
- Identification of a Novel δOR Selective Agonist Chemotype, Notably Devoid of a Basic Nitrogen
The FASEB Journal · 2021
- Isolation and Pharmacological Characterization of Six Opioidergic <i>Picralima nitida</i> Alkaloids
Journal of Natural Products · 2020
- Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids
ChemRxiv · 2020
- ChemRxiv×5
- Journal of Medicinal Chemistry×3
- The FASEB Journal×3
- bioRxiv (Cold Spring Harbor Laboratory)×2
- British Journal of Pharmacology×1
- Maryam Ghazala
Pharmacology, Toxicology and Pharmaceutics · The Ohio State University
- Richard M. van Rijn
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Ravi Jangir
Chemistry · Indiana University
- Robert J. Cassell
Neuroscience · Purdue University West Lafayette
- S. William Pelletier
Pharmacology, Toxicology and Pharmaceutics · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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