Publications
25
Citations
290
Est. group size
~3
Recurring co-author estimate
Active years
14
Publishing since 2013
Anil Kumar Marapaka's research focuses on designing and structurally characterizing small-molecule inhibitors that block enzymes used by pathogens (bacteria and malaria parasites) to survive or cause disease, such as carbonic anhydrases and aminopeptidases. This work combines medicinal chemistry (making and optimizing candidate drug molecules) with structural biology (using crystal structures to see how inhibitors bind their targets) to support development of new antibacterial and antimalarial treatments. Recent work has extended to using nanotechnology-based approaches for environmental applications.
Publication output was higher around 2017-2018 (5-7 papers/year) and has since slowed to roughly 0-2 papers per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Structure-Activity Relationship Studies for 1,3,4-Thiadiazole-Based Bacterial Carbonic Anhydrase Inhibitors with <i>In Vivo</i> Efficacy against Drug-Resistant <i>Neisseria gonorrhoeae</i>
Journal of Medicinal Chemistry · 2026
- Hit-to-Lead Optimization of Acetazolamide-Based Bacterial Carbonic Anhydrase Inhibitors with Efficacy In Vivo for Treatment of Vancomycin-Resistant Enterococci Septicemia
Journal of Medicinal Chemistry · 2025
- Implications of Nanotechnology for Environmental Remediation
2025
- Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates
Journal of Enzyme Inhibition and Medicinal Chemistry · 2023
- Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to <i>Neisseria gonorrhoeae</i> α-Carbonic Anhydrase
ACS Medicinal Chemistry Letters · 2022
- Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against <i>Neisseria gonorrhoeae</i>
ACS Infectious Diseases · 2021
- Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization
Chinese Chemical Letters · 2021
- Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
International Journal of Biological Macromolecules · 2020
- Discovery of a new class of type 1 methionine aminopeptidases that have relaxed substrate specificity
International Journal of Biological Macromolecules · 2019
- Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis
Biochemical Journal · 2019
- Single Pot Green Synthesis, Characterization, Antitumor Antibacterial, Antioxidant Activity of Bimetallic Silver and Copper Nanoparticles Using Fruit Pulp of Palmyra Fruit
Journal of Bionanoscience · 2018
- Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases
Molecules · 2018
- Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila
International Journal of Biological Macromolecules · 2018
- Crystal structure of Legionella pneumophila aminopeptidase A
2018
- Crystal structure of Legionella pneumophila aminopeptidase A in complex with glutamic acid
2018
- International Journal of Biological Macromolecules×3
- Journal of Medicinal Chemistry×2
- Acta Crystallographica Section A Foundations and Advances×2
- ACS Infectious Diseases×1
- Journal of Bionanoscience×1
- Varshini Are
Medicine · Purdue University West Lafayette
- Yi-Hsun Ho
Medicine · Purdue University West Lafayette
- Özlem Doǧan Ekici
Medicine · The Ohio State University
- Kiet T. Nguyen
Medicine · The Ohio State University
- Julia Grace Reinke
Medicine · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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