Andy P. Tsai
Neuroscience · Indiana University
Publications
79
Citations
3,096
Est. group size
—
Recurring co-author estimate
Active years
15
Publishing since 2012
Andy P. Tsai studies how the brain's immune cells (especially microglia) and inflammation contribute to aging, cognitive decline, and Alzheimer's disease. Much of the work uses genetics (such as the PLCG2, TREM2, and APOE genes), single-cell and spatial transcriptomics (measuring gene activity in individual cells while preserving location information), and advanced tissue imaging techniques. The research also spans mitochondrial biology, oxidative stress, and immune signaling in conditions like brain cancer.
Publication activity has been consistently high over the past decade, with an early rise, a peak in 2022, and a sustained pace of roughly ten papers per year in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Typically publishes in teams of ~9 · 0% small-team papers (≤3 authors) · across 33 venues
- The GLP ‐1–Mitochondria Axis in Metabolic Aging
Aging Cell · 2026
- Toward actionable interventions in human aging (12th ARDD meeting, 2025)
Aging · 2026
- Mitoxyperilysis: Rethinking oxidative stress as a spatially constrained lethal signal
International Journal of Biological Sciences · 2026
- PLCG2 signaling and genetic resilience in Alzheimer’s disease
Molecular Neurodegeneration · 2026
- Author Reply to Peer Reviews of Cross-Species Transcriptomic Integration Reveals a MIRO1-Mediated Macrophage-to-T Cell Signaling Axis Alginging with Immunosuppression in Glioma
2026
- Spatially gated oxidative killing: mitoxyperilysis redefines how ROS cause lytic cell death
APOPTOSIS · 2026
- Simultaneous spatial transcriptomics and morphology profiling as tools to explore how microglia change with age
Nature Aging · 2026
- Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
Immunity · 2026
- Mitochondrial quality control as a central pharmacological target in aging
Pharmacological Research · 2026
- Cross-species transcriptomic integration reveals a MIRO1-mediated macrophage–T cell axis in glioma
Life Science Alliance · 2026
- Cross-Species Transcriptomic Integration Reveals a MIRO1-Mediated Macrophage–T Cell Axis in Glioma
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Spatial and molecular insights into microglial roles in cerebellar aging
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Color-neutral and reversible tissue transparency enables longitudinal deep-tissue imaging in live mice
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology
Alzheimer s & Dementia · 2025
- Alzheimer s & Dementia×13
- bioRxiv (Cold Spring Harbor Laboratory)×11
- Scientific Reports×3
- Cellular Physiology and Biochemistry×2
- Genome Medicine×2
- Jie Gao
Neuroscience · The Ohio State University
- Luke C. Dabin
Neuroscience · Indiana University
- Kaylee D. Tutrow
Neuroscience · Indiana University
- Holly M. Brothers
Neuroscience · The Ohio State University
- Nicole D. Schartz
Neuroscience · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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