Andy J. Fischer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
160
Citations
8,024
Est. group size
~8
Recurring co-author estimate
Active years
47
Publishing since 1980
Andy J. Fischer's research investigates how the retina, the light-sensing tissue at the back of the eye, can regenerate damaged neurons using support cells called Müller glia, which in some animals (like chickens and zebrafish) can reprogram into progenitor-like cells that make new neurons. The lab studies the signaling pathways (such as NF-κB, cannabinoid, retinoic acid, and Jak/Stat pathways) and immune/glial responses that control whether this regenerative process happens, comparing species that regenerate well (birds, fish) to mammals that largely do not. This work aims to identify molecular targets that might eventually help restore vision after retinal injury or disease.
Publication output has grown over the past decade, rising from single-digit yearly counts in the late 2010s to a sustained higher level of 7-9 papers per year in 2023-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Enteroendocrine cells wire the gut–brain vagal axis
Proceedings of the National Academy of Sciences · 2026
- <scp>NFkB</scp> ‐signaling promotes glial reactivity and suppresses Müller glia‐mediated neuron regeneration in the mammalian retina
Glia · 2022
- Cover Image, Volume 70, Issue 7
Glia · 2022
- Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia‐derived progenitor cells in chick and mouse retinas
Glia · 2021
- Cannabinoid signaling promotes the de‐differentiation and proliferation of Müller glia‐derived progenitor cells
Glia · 2021
- NFkB-signaling promotes glial reactivity and suppresses Müller glia-mediated neuron regeneration in the mammalian retina
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Cannabinoid signaling promotes the reprogramming of Muller glia into proliferating progenitor cells
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Gene regulatory networks controlling vertebrate retinal regeneration
Science · 2020
- NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina
Development · 2020
- Midkine in chick and mouse retinas: neuroprotection, glial reactivity and the formation of Müller glia-derived progenitor cells
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina
Journal of Neuroinflammation · 2019
- Avian Adeno-Associated Viral Transduction of the Postembryonic Chicken Retina
Translational Vision Science & Technology · 2019
- Sildenafil Administration in Dogs Heterozygous for a Functional Null Mutation in Pde6a: Suppressed Rod-Mediated ERG Responses and Apparent Retinal Outer Nuclear Layer Thinning
Advances in experimental medicine and biology · 2019
- Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas
bioRxiv (Cold Spring Harbor Laboratory) · 2019
- NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina
bioRxiv (Cold Spring Harbor Laboratory) · 2019
- bioRxiv (Cold Spring Harbor Laboratory)×15
- Glia×10
- eLife×5
- Development×4
- Journal of Neuroscience×2
- Andrew J Fischer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Shahna Shahul Hameed
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jade Harkin
Biochemistry, Genetics and Molecular Biology · Indiana University
- Kang-Chieh Huang
Biochemistry, Genetics and Molecular Biology · Indiana University
- Tasneem P. Sharma
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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