Publications
117
Citations
1,349
Est. group size
—
Recurring co-author estimate
Active years
20
Publishing since 2007
Andrea L. Frump studies pulmonary hypertension, a condition of high blood pressure in the lung arteries, with a focus on how the right side of the heart fails or adapts under this stress. A recurring theme is how sex hormones, especially estrogen and estrogen receptor alpha, influence blood vessel growth, cell metabolism, and inflammation in the right ventricle, often differing between males and females. The work combines molecular biology, cell studies, and animal models to explore potential diagnostic and therapeutic targets.
Publication activity has been fairly steady at roughly 6-10 papers per year over the past decade, with a notable one-year spike in 2023.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through July 2027 — about under a year of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
The emerging role of apelin, RAAS, and ACE2 crosstalk in pulmonary hypertension
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~8 · 14% small-team papers (≤3 authors) · across 21 venues
- Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics
British Journal of Biomedical Science · 2026
- Cardiomyocyte NLRP3 signaling in right heart failure is sexually dimorphic via estrogen receptor α
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- 17β-Estradiol Promotes Right Ventricle Angiogenesis via Estrogen Receptor α and Apelin Signaling
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension
Circulation Research · 2025
- Abstract 4365971: Estrogen receptor alpha inhibits right ventricle cardiomyocyte NLRP3 inflammasome activation and restores right ventricular contractile function in low estrogen states
Circulation · 2025
- Sexually dimorphic role of estrogen receptor α in preserving right ventricular endothelial integrity
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Reveals Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension
Journal of Respiratory Biology and Translational Medicine · 2025
- 17β-estradiol Enhances Right Ventricle Angiogenesis and Endothelial Cell Fatty Acid Oxidation in PAH in a Carnitine Palmitoyltransferase 1-dependent Manner
American Journal of Respiratory and Critical Care Medicine · 2025
- NLRP3-induced Contractile Dysfunction in Right Ventricle Cardiomyocytes Is Sexually Dimorphic and Modified by 17β-estradiol Via Estrogen Receptor α
2024
- Heartbreaking Ends: Unraveling the Significance of Alternative Polyadenylation in Right Ventricular Failure
2024
- Abstract 4142930: Title: Loss of estrogen receptor α causes early onset of right ventricular capillary rarefaction in female rats with experimental pulmonary hypertension
Circulation · 2024
- 17β-estradiol Enhances Right Ventricle Angiogenesis and Endothelial Cell Fatty Acid Metabolism in Pulmonary Arterial Hypertension in a CPT1-dependent Manner
2024
- Pathophysiology and new advances in pulmonary hypertension
BMJ Medicine · 2023
- Wnt7a deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension
European Respiratory Journal · 2023
- Supplementary Figures S2 and S3 from Targeting the Wnt Pathway in Synovial Sarcoma Models
2023
- Circulation×12
- PMC×6
- American Journal of Respiratory and Critical Care Medicine×5
- Medicine & Science in Sports & Exercise×5
- American Journal of Respiratory Cell and Molecular Biology×4
- Scott Visovatti
Medicine · The Ohio State University
- Rebecca Vanderpool
Medicine · The Ohio State University
- Priscilla Correa‐Jaque
Medicine · The Ohio State University
- Todd Cook
Medicine · Indiana University
- Ankit A. Desai
Medicine · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
Claim or correct this profile