Alexander Röth
Immunology and Microbiology · Purdue University West Lafayette
Publications
238
Citations
11,304
Est. group size
—
Recurring co-author estimate
Active years
59
Publishing since 1968
Alexander Röth's research focuses on rare blood disorders involving abnormal destruction of red blood cells and blood clotting problems, particularly paroxysmal nocturnal hemoglobinuria (PNH), cold agglutinin disease, aplastic anemia, and sickle cell disease. Much of the work involves clinical trials testing drugs that block or modulate the complement system, a part of the immune system that can mistakenly attack a patient's own blood cells, as well as studies on treatment safety, effectiveness, and patient-reported quality of life. This research is largely conducted through multi-site clinical trials and registries evaluating new and existing therapies for these conditions.
Publication output has grown substantially over the past decade, rising from single digits in 2017 to a sustained level of roughly 20-30 papers per year since 2023.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Safety and efficacy of voxelotor in adult patients with sickle cell disease
Blood Red Cells & Iron · 2026
- Ravulizumab demonstrates long-term efficacy, safety and favorable patient survival in patients with paroxysmal nocturnal hemoglobinuria
Annals of Hematology · 2025
- Late-onset telomere biology disorders in adults: clinical insights and treatment outcomes from a retrospective registry cohort
Blood Advances · 2025
- Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria
British Journal of Clinical Pharmacology · 2025
- Characterizing clinically significant extravascular hemolysis in adults with PNH on ravulizumab or eculizumab treatment
Blood Advances · 2025
- Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors
The Lancet Haematology · 2025
- Managing transient immune complex reactions in patients with paroxysmal nocturnal hemoglobinuria: clinical observations from the COMMODORE 1 and 2 studies
Therapeutic Advances in Hematology · 2025
- Patient-reported outcomes in patients with paroxysmal nocturnal hemoglobinuria treated with crovalimab and approved C5 inhibitors in the phase III COMMODORE 2 and 1 studies
Annals of Hematology · 2025
- Cobalamin and iron deficiency still presents a challenge in hereditary hemorrhagic telangiectasia
Scientific Reports · 2025
- Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial
American Journal of Hematology · 2025
- FACIT-Fatigue scale in patients with cold agglutinin disease: psychometric validation and estimation of clinically meaningful change
Frontiers in Hematology · 2025
- Nichtneoplastische Erkrankungen
2025
- Kälteagglutininerkrankung
Die Innere Medizin · 2025
- Switching between complement inhibitors in patients with PNH: A real-world analysis of strategy, efficacy, and safety.
Blood · 2025
- Serum ferritin changes in iptacopan-treated patients with paroxysmal nocturnal hemoglobinuria
Blood · 2025
- Blood×44
- European Journal Of Haematology×15
- HemaSphere×13
- Annals of Hematology×9
- The Lancet Haematology×7
- Spero R. Cataland
Immunology and Microbiology · The Ohio State University
- Shangbin Yang
Immunology and Microbiology · The Ohio State University
- Spero Cataland
Immunology and Microbiology · The Ohio State University
- Margaret M. Fitzpatrick
Immunology and Microbiology · The Ohio State University
- Melissa J. Rose
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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