Aleksander Skardal
Engineering · The Ohio State University
Publications
139
Citations
10,766
Est. group size
~15
Recurring co-author estimate
Active years
20
Publishing since 2007
Aleksander Skardal's research focuses on building 3D, lab-grown tissue and tumor models made from engineered hydrogels to study cancers such as glioblastoma, adrenocortical carcinoma, osteosarcoma, and pancreatic cancer, as well as organ-on-a-chip systems that mimic organs like the lung and blood-brain barrier. This work aims to better replicate how tumors interact with surrounding tissue, immune cells, and drugs, supporting research into cancer biology and preclinical drug testing. Students in this group would likely work on bioengineering tissue-mimicking devices and testing therapeutic responses using patient-derived cells.
Publication output has gradually declined over the last decade, from a peak of about 18 papers per year around 2018 to roughly 4-7 per year in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Establishment of a patient-derived adrenocortical carcinoma 3D tumor construct platform for evaluation of therapeutic strategies
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Hyaluronan-Based Glioblastoma Tumor Constructs Maintain Patient Tumor Drug Responses and Genomic Parity
Micromachines · 2026
- Characterization of a hybrid hydrogel for the studying of lymphocyte infiltration and migration in a 3-dimensional <i>in vitro</i> tumor stroma device
Biofabrication · 2026
- Engineering a 3D Lung Co-culture Platform to Model Epithelial–Fibroblast Interactions in Pulmonary Fibrosis
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- A Microfluidic Blood Brain Barrier Model to Study the Influence of Glioblastoma Tumor Cells on BBB Function
Small · 2025
- Evaluation of natural killer cell tumor homing and effector function in response to CDK4/6 and AURKA inhibition in a melanoma tumor-on-a-chip platform
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Fibroblasts drive differential response in immunotherapy via IL-6 in bioengineered 3D cancer constructs
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Profiling Magnetically Sorted Glioblastoma Cells Using Extracellular Matrix-Mimicking Integrin-Targeting Probes
SSRN Electronic Journal · 2025
- Grand challenges in organoid and organ-on-a-chip technologies
Frontiers in Bioengineering and Biotechnology · 2024
- RCAN1.4 regulates tumor cell engraftment and invasion in a thyroid cancer to lung metastasis-on-a-chip microphysiological system
Biofabrication · 2024
- Bioengineered in vitro three-dimensional tumor models in endocrine cancers
Endocrine Related Cancer · 2024
- A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation
Cellular and Molecular Bioengineering · 2024
- Abstract B097: Tomatidine inhibits ATF4 activity and induces ferroptosis to limit pancreatic cancer progression
Cancer Research · 2024
- Tuning a bioengineered hydrogel for studying astrocyte reactivity in glioblastoma
Acta Biomaterialia · 2024
- Tuning a Bioengineered Hydrogel for Studying Astrocyte Reactivity in Glioblastoma
SSRN Electronic Journal · 2024
- Elsevier eBooks×8
- Annals of Surgical Oncology×7
- bioRxiv (Cold Spring Harbor Laboratory)×7
- Scientific Reports×6
- Biofabrication×5
- Bumsoo Han
Engineering · Purdue University West Lafayette
- Hye‐ran Moon
Engineering · Purdue University West Lafayette
- Alex Avendano
Engineering · The Ohio State University
- Jonathan W. Song
Engineering · The Ohio State University
- Marcos Cortes-Medina
Engineering · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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