LabCompass

A. Douglas Kinghorn

Biochemistry, Genetics and Molecular Biology · The Ohio State University

OpenAlex ORCID
Established · publishing since 1973
Natural product bioactivities and synthesisPhytochemical compounds biological activitiesPhytochemistry and Biological ActivitiesTraditional and Medicinal Uses of AnnonaceaeBioactive natural compounds

Publications

846

Citations

38,902

Est. group size

~11

Recurring co-author estimate

Active years

54

Publishing since 1973

Research summary
AI-generated

This researcher focuses on discovering and studying natural compounds from plants and fungi that show potential as anticancer, antitumor, and other therapeutic agents, particularly examining how molecules like cardiac glycosides and lignans interact with biological targets such as the Na+/K+-ATPase enzyme. Much of the work involves isolating novel chemicals from plant sources, testing their activity against cancer cells (including ovarian cancer and osteosarcoma), and understanding their chemical structures. This research combines chemistry, pharmacology, and traditional medicine knowledge to identify candidate drugs from nature.

Natural product drug discoveryCancer cell toxicity and cancer prevention compoundsPlant and fungal phytochemistryCardiac glycosides and enzyme interactionsStructure-activity relationships of bioactive compounds

Publication output has been relatively steady over the past decade with some year-to-year fluctuation, though recent years (2024-2025) show a modest decline compared to a peak in 2023.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 10.6/year recently
2017: 12 publications172018: 18 publications182019: 16 publications192020: 13 publications202021: 15 publications212022: 11 publications222023: 20 publications20232024: 11 publications242025: 10 publications252026: 1 publication26
Recent publications
Publishes in
  • Journal of Natural Products×24
  • Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products×18
  • Planta Medica×11
  • Molecules×7
  • Bioorganic & Medicinal Chemistry×7
Similar researchers
By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

Claim or correct this profile